In order to investigate the effect of chitosan/pshRNA plasmid nanoparticles targeting MDR1
genes on the resistance of A2780/TS cells to paclitaxel, chitosan/pshRNA plasmid …

In order to investigate the effects of vector-based hairpin small interference RNA (shRNA) on
the reversal of multi-drug resistance (mdr) of A2780/Taxol cells, a novel vector pEGFP …

Objective Recurrent ovarian cancer is often resistant to drugs such as paclitaxel. Short
hairpin RNA (shRNA) targeting MDR1, a gene involved in the process of drug resistance …

Background: To explore the effects of downregulated multidrug-resistance P-glycoprotein
(MDR1/ABCB1) and reversed multidrug-resistance in human A2780 ovarian cancer cells …

Multidrug resistance (MDR) remains the major obstacle to the success of clinical cancer
chemotherapy. P-glycoprotein (P-gp), encoded by the MDR1, is an important part with …

Objective To evaluate the effects of siRNA on the inhibitions of mRNA and P-gp expression
of ovarian cancer cell with high expression of multidrug resistance gene (MDR1). Methods …

Purpose The aim of this study was to test the ability of paclitaxel-loaded poly
(butylcyanoacrylate)(PBCA) nanoparticles to overcome multidrug resistance (MDR) in …

Objective To investigate the effects of small interference RNA (siRNA) on the inhibition of
MDR1 mRNA and P-gp expression of ovarian cancer cells with high expression of MDR1 …

The aim of the present study was to evaluate the efficacy of paclitaxel combined with
curcumin (CUR) against drug resistance in ovarian cancer cells. PLGA-phospholipid-PEG …

In this study, the effect of MDR-1 gene silencing, using small interfering RNA (siRNA), and
paclitaxel (PTX) co-therapy in overcoming tumor multidrug resistance was examined. Poly …