Antiproliferative and antioxidative effects of novel hydrazone derivatives bearing coumarin and chromene moiety
VT Angelova, NG Vassilev… - Medicinal Chemistry …, 2016 - Springer
A series of new hybrid molecules with a hydrazone fragment were synthesized and
characterized by Fourier transform-infrared spectroscopy, nuclear magnetic resonance …
characterized by Fourier transform-infrared spectroscopy, nuclear magnetic resonance …
New2-((2-(2,4-dinitrophenyl)hydrazineeylidene) derivatives: design, synthesis, in silico, and in vitro anticancer studies
A series of novel hydrazone compounds have been synthesized by the condensation of
hydrazines and different substituted salicylaldehydes at a molar ratio of 1: 1 in one step …
hydrazines and different substituted salicylaldehydes at a molar ratio of 1: 1 in one step …
[HTML][HTML] Oxamic acid thiohydrazides and hydrazones based on them as convenient starting compounds for the synthesis of S-and N-containing heterocyclic products …
MM Krayushkin, VN Yarovenko - Arabian Journal of Chemistry, 2024 - Elsevier
The chemistry of hydrazones is currently undergoing intensive development. For example,
thioacylhydrazones, which are synthesized most often from thiosemicarbazides, have …
thioacylhydrazones, which are synthesized most often from thiosemicarbazides, have …
Synthesis of Novel Hydrazide–Hydrazone Compounds and In Vitro and In Silico Investigation of Their Biological Activities against AChE, BChE, and hCA I and II
The abnormal levels of the human carbonic anhydrase isoenzymes I and II (hCA I and II)
and cholinesterase enzymes, namely, acetylcholinesterase (AChE) and …
and cholinesterase enzymes, namely, acetylcholinesterase (AChE) and …
Synthesis, structure–activity relationship studies using density functional theory and in silico molecular docking on substituted benzohydrazide derivatives
The present study demonstrates the utility of benzohydrazide derivatives based on an
approach to identify potential targets for a series of synthesized compounds that show potent …
approach to identify potential targets for a series of synthesized compounds that show potent …
Hydrazone comprising compounds as promising anti-infective agents: Chemistry and structure-property relationship
Despite the adverse effects of microbial hazards on public health, major pharmaceutical
firms have left the field of anti-infective development and a dramatic reduction in the number …
firms have left the field of anti-infective development and a dramatic reduction in the number …
[PDF][PDF] Hydrazones as promising lead with diversity in bioactivity-therapeutic potential in present scenario
S Bala, G Uppal, A Kajal, S Kamboj… - Int J Pharm Sci Rev …, 2013 - academia.edu
Hydrazones is an important class of compounds for the development of novel drug moieties.
Hydrazones consists of an azomethine-NHN= CH-proton which is responsible for the …
Hydrazones consists of an azomethine-NHN= CH-proton which is responsible for the …
[HTML][HTML] Synthesis, crystal structure and bioactivity of phenazine-1-carboxylic acylhydrazone derivatives
S Wu, X Liang, F Luo, H Liu, L Shen, X Yang, Y Huang… - Molecules, 2021 - mdpi.com
A phenazine-1-carboxylic acid intermediate was synthesized from the reaction of aniline and
2-bromo-3-nitro-benzoic acid. It was then esterified and reacted with hydrazine hydrate to …
2-bromo-3-nitro-benzoic acid. It was then esterified and reacted with hydrazine hydrate to …
Synthesis of Novel N-Acylhydrazones and Their CN/NN Bond Conformational Characterization by NMR Spectroscopy
In this article, a synthesis of N'-(benzylidene)-2-(6-methyl-1 H-pyrazolo [3, 4-b] quinolin-1-yl)
acetohydrazides and their structural interpretation by NMR experiments is described in an …
acetohydrazides and their structural interpretation by NMR experiments is described in an …
Development of Novel Indazolyl‐Acyl Hydrazones as Antioxidant and Anticancer Agents that Target VEGFR‐2 in Human Breast Cancer Cells
SM Parameshwaraiah, R Shivakumar… - Chemistry & …, 2024 - Wiley Online Library
The increased expression of VEGFR‐2 in a variety of cancer cells promotes a cascade of
cellular responses that improve cell survival, growth, and proliferation. Heterocycles are …
cellular responses that improve cell survival, growth, and proliferation. Heterocycles are …