Bet v 1 is the major birch pollen allergen. A highly efficient expression and purification
scheme for mutant forms of this protein was developed on the basis of the pET expression …

Bet v 1, the major allergen of birch pollen, displays a considerable degree of heterogeneity.
Several charge variants have been detected by two-dimensional IgE immunoblots and …

A gene encoding the pollen major allergen Bet v 1 fromBetula verrucosa (White Birch) has
been cloned and expressed inEscherichia colias a fusion with maltose-binding protein and …

In 2D-PAGE analysis of Bet v 1, the major birch pollen allergen, up to 12 isoforms can be
demonstrated that differ in their isoelectric points from about pH 4.9 to pH 5.9. The molecular …

The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens
Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology …

Bet v 1, the major pollen allergen from white birch, displays a considerable degree of
heterogeneity. Until now, all molecular and immunological characterization studies of Bet v 1 …

The 17 kDa protein from Betula verrucosa (White Birch) pollen, Bet v 1, is the clinically most
important birch pollen allergen causing immediate Type I IgE‐mediated allergy. The three …

Bet v 1 is the major birch pollen allergen and therefore the main cause of type I allergies
observed in early spring. It is composed of 159 amino acid residues adding up to a …

Bet v I, the major allergen of birch pollen, is a 17 kD cytosolic protein that is quantitatively
extracted from pollen grains by simply washing with water. The cDNA sequence¹ of Bet v I …

Pollen from trees of the order Fagales (eg birch, alder, hazel, oak, and hornbeam) are a
major cause of Type I allergies observed in early spring. Previously, we reported the cloning …