Genomic characterization of members of the Bet v 1 family: genes coding for allergens and pathogenesis-related proteins share intron positions
K Hoffmann-Sommergruber, M Vanek-Krebitz… - Gene, 1997 - Elsevier
Bet v 1, the major birch pollen allergen, is a member of a multigene family; a number of
isoforms and homologous proteins from closely related species (alder, hazel and hornbeam) …
isoforms and homologous proteins from closely related species (alder, hazel and hornbeam) …
The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands
JE Mogensen, R Wimmer, JN Larsen… - Journal of Biological …, 2002 - ASBMB
Bet v 1 is a 17-kDa protein abundantly present in the pollen of the White birch tree and is the
primary cause of birch pollen allergy in humans. Its three-dimensional structure is …
primary cause of birch pollen allergy in humans. Its three-dimensional structure is …
Profiling preparations of recombinant birch pollen allergen Bet v 1a with capillary zone electrophoresis in pentamine modified fused-silica capillaries
M Punzet, F Ferreira, P Briza, R van Ree… - … of Chromatography B, 2006 - Elsevier
Three preparation batches of the recombinant birch pollen allergen Bet v 1a have been
analyzed by capillary zone electrophoresis (CZE) using a separation electrolyte consisting …
analyzed by capillary zone electrophoresis (CZE) using a separation electrolyte consisting …
Bet v 1 proteins, the major birch pollen allergens and members of a family of conserved pathogenesis‐related proteins, show ribonuclease activity in vitro
I Swoboda, K Hoffmann‐Sommergruber… - Physiologia …, 1996 - Wiley Online Library
The Bet v. 1 gene family of birch encodes the major pollen allergens as well as
pathogenesis‐related (PR) proteins that are induced by microbes in somatic tissues. These …
pathogenesis‐related (PR) proteins that are induced by microbes in somatic tissues. These …
Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy
T Batard, A Didierlaurent, H Chabre, N Mothes… - International archives of …, 2005 - karger.com
Background: We describe the production in Escherichia coli as a recombinant protein of
clinical grade wild-type Bet v 1a (rBet v 1a), to be used as a candidate vaccine against birch …
clinical grade wild-type Bet v 1a (rBet v 1a), to be used as a candidate vaccine against birch …
[HTML][HTML] Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen bet v 1
S Kofler, C Asam, U Eckhard, M Wallner… - Journal of molecular …, 2012 - Elsevier
The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands
is considered to play a key role for their physiological and pathological functions. In …
is considered to play a key role for their physiological and pathological functions. In …
Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier
Bet v 1l is a naturally occurring hypoallergenic isoform of the major birch pollen allergen Bet
v 1. The Bet v 1 protein belongs to the ubiquitous family of pathogenesis-related plant …
v 1. The Bet v 1 protein belongs to the ubiquitous family of pathogenesis-related plant …
Seven different genes encode a diverse mixture of isoforms of Bet v 1, the major birch pollen allergen
MF Schenk, LJWJ Gilissen, GD Esselink… - BMC genomics, 2006 - Springer
Abstract Background Pollen of the European white birch (Betula pendula, syn. B. verrucosa)
is an important cause of hay fever. The main allergen is Bet v 1, member of the pathogenesis …
is an important cause of hay fever. The main allergen is Bet v 1, member of the pathogenesis …
Ligand recognition of the major birch pollen allergen Bet v 1 is isoform dependent
C Seutter von Loetzen, T Jacob, O Hartl-Spiegelhauer… - PLoS …, 2015 - journals.plos.org
Each spring millions of patients suffer from allergies when birch pollen is released into the
air. In most cases, the major pollen allergen Bet v 1 is the elicitor of the allergy symptoms …
air. In most cases, the major pollen allergen Bet v 1 is the elicitor of the allergy symptoms …
The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes
JE Mogensen, M Ferreras, R Wimmer, SV Petersen… - Biochemistry, 2007 - ACS Publications
The 159 residue Bet v 1 is the major allergen from birch tree pollen. Its natural function is
unknown although it is capable of binding several types of physiologically relevant ligands …
unknown although it is capable of binding several types of physiologically relevant ligands …