Previously, defined naturally occurring isoforms of allergenic proteins were classified as
hypoallergens and therefore suggested as an agent for immunotherapy in the future. In this …

Type I allergies are immunological disorders that afflict a quarter of the world's population.
Improved diagnosis of allergic diseases and the formulation of new therapeutic approaches …

Two monoclonal antibodies against birch pollen proteins were produced by immunizing
BALB/c mice with birch pollen extract. In immunoblotting experiments, antibody BIP 1 …

The major birch pollen allergen Bet v 1 is one of the most extensively characterized
allergens both on the molecular and the immunological level. To define conformational B …

Allergic diseases, such as hay fever and food allergy, affect a substantial part of the
population in westernized countries. Pollen of the European white birch (Betula pendula) is …

The major birch pollen allergen, Betv1 of Betula verrucosa is the main causative agent of
birch pollen allergy in humans. Betv1 is capable of binding several physiological ligands …

Type I allergy, an immunodisorder affecting almost 20% of the population worldwide, is
based on the production of IgE antibodies against per se harmless allergens. We report the …

Pathogenesis-related plant proteins of class-10 (PR-10) are essential for storage and
transport of small molecules. A prominent member of the PR-10 family, the major birch …

Confocal laser scanning microscopy (CLSM) was used to localize the major allergen, Bet v I
in birch pollen. Pollen grains of Belula pendula were collected from catkins that had begun …

To date, the potency of allergen products in Europe is expressed in manufacturer-specific
units relative to a product-specific in-house reference. Consequently, cross-product …