Nitric oxide and other reactive nitrogen species appear to play several crucial roles in the
brain. These include physiological processes such as neuromodulation, neurotransmission …

Nitric oxide (NO) is a pleiotropic janus-faced molecule synthesized by nitric oxide synthases
(NOS) which plays a critical role in a number of physiological and pathological processes in …

Besides its role as a mediator of several physiological functions, nitric oxide appears to be a
neurotoxin under conditions of excessive production, which suggests a role for nitric oxide in …

Inducible nitric oxide synthase (iNOS) is one of three NOS isoforms generating nitric oxide
(NO) by the conversion of l-arginine to l-citrulline. iNOS has been found to be a major …

The management of neurological disorders have huge and increasing human and economic
costs. Despite this, there is a scarcity of effective therapeutics, and there is an extreme …

Nitric oxide (NO) is a molecule with pleiotropic effects in different tissues. NO is synthesized
by NO synthases (NOS), a family with four major types: endothelial, neuronal, inducible and …

Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …

Nitric oxide (NO) is involved in important physiological functions of the CNS, including
neurotransmission, memory and synaptic plasticity. Depending on the redox state of NO, it …

The accumulation and propagation of misfolded proteins in the brain is a pathological
hallmark shared by many neurodegenerative diseases, such as the depositions of β-amyloid …

Nitric oxide (NO) is a versatile cellular messenger performing a variety of physiologic and
pathologic actions in most tissues. It is particularly important in the nervous system, where it …