Nitric oxide (NO) is an important regulatory molecule for the host defense that plays a
fundamental role in the cardiovascular, immune, and nervous systems. NO is synthesized …

As a signal molecule, nitric oxide (NO) plays an important role in a variety of signal
transduction pathways that are crucial for maintaining the physiologic functions of vascular …

Nitric oxide (NO) is a multifunctional signalling molecule and a neurotransmitter that plays
an important role in physiological and pathophysiological processes. In physiological …

Publisher Summary A variety of mechanisms have been proposed for NO neurotoxicity,
including inhibition of mitochondrial enzymes such as cis-aconitase, inhibition of the …

Elevated levels of NO produced within the central nervous system (CNS) are associated with
the pathogenesis of neuroinflammatory and neurodegenerative human diseases such as …

There is increasing evidence that nitric oxide (NO), a free radical that can act both as a
signaling molecule and a neurotoxin, is involved in the mechanisms of cerebral ischemia …

Nitric oxide (NO), an enzymatic product of nitric oxide synthase (NOS), has been associated
with a variety of neurological diseases such as Alzheimer's disease (AD). NO has long been …

Nitric oxide (NO) is a widespread and multifunctional biological messenger molecule. It
mediates vasodilation of blood vessels, host defence against infectious agents and tumors …

Alzheimer's disease (AD) constitutes a progressive neurodegenerative disorder and the
main cause of dementia. Numerous studies have focused on the pathogenic mechanism of …

During the last decades nitric oxide (• NO) has emerged as a critical physiological signaling
molecule in mammalian tissues, notably in the brain.• NO may modify the activity of …