Nitric oxide-derived oxidants with a focus on peroxynitrite: molecular targets, cellular responses and therapeutic implications

P Calcerrada, G Peluffo, R Radi - Current pharmaceutical …, 2011 - ingentaconnect.com
Nitric oxide participates in a wide array of physiological processes, ranging from
neurotransmission to precursor of cytotoxic effector molecules of the immune system …

Nitric oxide, cell bioenergetics and neurodegeneration

S Moncada, JP Bolaños - Journal of neurochemistry, 2006 - Wiley Online Library
Following stimulation of NMDA receptors, neurons transiently synthesize nitric oxide (NO) in
a calcium/calmodulin‐dependent manner through the activation of neuronal NO synthase …

[HTML][HTML] Nitric oxide neurotoxicity

VL Dawson, TM Dawson - Journal of chemical neuroanatomy, 1996 - Elsevier
Derangements in glutamate neurotransmission have been implicated in several
neurodegenerative disorders including, stroke, epilepsy, Huntington's disease, Alzheimer's …

[图书][B] Nitric oxide in health and disease

J Lincoln, CHV Hoyle, G Burnstock - 1997 - books.google.com
Nitric oxide has a tantalizing role in health and disease: while many of its wide-ranging
effects are well known, there remains much more to explore and to learn about the …

Endogenous nitric oxide synthesis: biological functions and pathophysiology

DS Bredt - Free radical research, 1999 - Taylor & Francis
Modern molecular biology has revealed vast numbers of large and complex proteins and
genes that regulate body function. By contrast, discoveries over the past ten years indicate …

[HTML][HTML] The bioactivity of neuronal-derived nitric oxide in aging and neurodegeneration: Switching signaling to degeneration

A Ledo, CF Lourenço, E Cadenas, RM Barbosa… - Free Radical Biology …, 2021 - Elsevier
The small and diffusible free radical nitric oxide (• NO) has fascinated biological and medical
sciences since it was promoted from atmospheric air pollutant to biological ubiquitous …

Nitric oxide, S-nitrosylation and neurodegeneration.

KK Chung, TM Dawson, VL Dawson - Cellular and molecular …, 2005 - europepmc.org
Nitric oxide is a critically important signaling molecule, controlling a wide range of pathways
and biological processes. Highly reactive nitric oxide mediates its function through reaction …

Physiological and pathophysiological roles of nitric oxide in the central nervous system

C Szabó - Brain research bulletin, 1996 - Elsevier
Nitric oxide (NO) is produced by three distinct isoforms of nitric oxide synthases in the central
nervous system. Here, the roles of nitric oxide in the central nervous system are reviewed …

Emerging roles of nitric oxide in neurodegeneration

KKK Chung, KK David - Nitric Oxide, 2010 - Elsevier
Nitric oxide (NO) is a gaseous signaling molecule which has physiological and pathological
roles in the cell. Under normal conditions, NO is produced by nitric oxide synthase (NOS) …

Brain iNOS: current understanding and clinical implications

J Licinio, P Prolo, SM McCann, ML Wong - Molecular medicine today, 1999 - cell.com
Nitric oxide (NO) is a unique informational substance first identified as the endothelium-
derived relaxing factor. It is generated by NO symthases and plays a prominent role in …