Nitric oxide in cell survival: a janus molecule

V Calabrese, C Cornelius, E Rizzarelli… - Antioxidants & Redox …, 2009 - liebertpub.com
Nitric oxide (NO), plays multiple roles in the nervous system. In addition to regulating
proliferation, survival and differentiation of neurons, NO is involved in synaptic activity …

Nitric oxide: a pleiotropic signal in the nervous system

EE Benarroch - Neurology, 2011 - AAN Enterprises
Nitric oxide (NO) is a gaseous chemical transmitter that is produced from the amino acid L-
arginine by the members of the NO synthase (NOS) family of proteins. NO is involved in …

Neurovascular-neuroenergetic coupling axis in the brain: master regulation by nitric oxide and consequences in aging and neurodegeneration

CF Lourenço, A Ledo, RM Barbosa… - Free Radical Biology and …, 2017 - Elsevier
The strict energetic demands of the brain require that nutrient supply and usage be fine-
tuned in accordance with the specific temporal and spatial patterns of ever-changing levels …

Nitric oxide related therapeutic phenomenon: a challenging task

MJ Alcaraz, MI Guillen - Current pharmaceutical design, 2002 - ingentaconnect.com
Nitric oxide (NO), produced from L-arginine by the activity of constitutive and inducible NO
synthases, has been implicated in a wide range of physiological and pathophysiological …

Physiological and toxicological actions of nitric oxide in the central nervous system

VL Dawson, TM Dawson - Advances in Pharmacology, 1995 - Elsevier
Publisher Summary Nitric Oxide (NO) has clearly revolutionized research about aspects of
neurotransmission and neuronal signaling. It has also radically altered studies about how …

Neuroinflammatory processes are important in neurodegenerative diseases: an hypothesis to explain the increased formation of reactive oxygen and nitrogen species …

RA Floyd - Free Radical Biology and Medicine, 1999 - Elsevier
The hypothesis, as stated in the title, has arisen from the failure of simpler notions to explain
a series of otherwise difficult to understand observations and the mounting evidence, in a …

NOX enzymes in the central nervous system: from signaling to disease

S Sorce, KH Krause - Antioxidants & redox signaling, 2009 - liebertpub.com
Oxidative stress has been implicated in the pathogenesis of neurologic and psychiatric
diseases. The brain is particularly vulnerable to oxidative damage due to high oxygen …

Alzheimer's disease: A contextual link with nitric oxide synthase

H Dubey, K Gulati, A Ray - Current Molecular Medicine, 2020 - ingentaconnect.com
Nitric oxide (NO) is a gasotransmitter with pleiotropic effects which has made a great impact
on biology and medicine. A multidimensional neuromodulatory role of NO has been shown …

Roles of nitric oxide synthase isoforms in neurogenesis

CM Chong, N Ai, M Ke, Y Tan, Z Huang, Y Li… - Molecular …, 2018 - Springer
Nitric oxide (NO), a free radical gas, acts as a neurotransmitter or neuromodulator in the
central nervous system (CNS). It has been widely explored as a mediator of …

Hippocampus and nitric oxide

Y Hu, DY Zhu - Vitamins & Hormones, 2014 - Elsevier
Since it was first identified to play an important role in relaxation of blood vessels, nitric oxide
has been demonstrated to regulate many biological processes, especially in the central …