Nitric oxide in the central nervous system

I Paakkari, P Lindsberg - Annals of medicine, 1995 - Taylor & Francis
The majority of the data on nitric oxide (NO) in the central nervous system (CNS) relies on
histochemical and immunesohistochemical evidence concerning the distribution of the nitric …

[PDF][PDF] Brain nitric oxide synthases and mitochondrial function

J Bustamante, A Czerniczyniec, S Lores-Arnaiz - Front Biosci, 2007 - researchgate.net
[Frontiers in Bioscience 12, 1034-1040, January 1, 2007] 1034 Brain nitric oxide synthases
and mitochondrial function Juanita Bu Page 1 [Frontiers in Bioscience 12, 1034-1040, January …

Nitric oxide synthase: role as a transmitter/mediator in the brain and endocrine system

TM Dawson, MD, Ph. D… - Annual review of …, 1996 - annualreviews.org
▪ Abstract Nitric oxide is a unique biological messenger molecule. It is produced by
endothelial cells to mediate blood vessel relaxation; it mediates, in part, the immune …

Nicotinamide adenine dinucleotide phosphate oxidase and neurodegenerative diseases: mechanisms and therapy

L Hou, L Zhang, JS Hong, D Zhang, J Zhao… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: The growing incidence of neurodegenerative diseases significantly impacts
the individuals who suffer from these disorders and is a major health concern globally …

[PDF][PDF] Stress-related diseases-a potential role for nitric oxide

T Esch, GB Stefano, GL Fricchione… - Medical Science …, 2002 - researchgate.net
Nitric oxide (NO) is involved in stress physiology and stress-related disease processes. Like
stress, NO seems to be capable of principally exerting either beneficial or deleterious effects …

Design of selective neuronal nitric oxide synthase inhibitors for the prevention and treatment of neurodegenerative diseases

RB Silverman - Accounts of chemical research, 2009 - ACS Publications
Nitric oxide (NO), which is produced from l-arginine by the nitric oxide synthase (NOS) family
of enzymes, is an important second-messenger molecule that regulates several …

Biochemical aspects of nitric oxide

S Mariotto, M Menegazzi… - Current pharmaceutical …, 2004 - ingentaconnect.com
Nitric oxide (NO), a free radical molecule, produced by NO synthase (NOS) in the body
exerts a number of pathophysiological actions due to its chemical reactivity. Low amounts of …

Nitric oxide‐mediated posttranslational modifications: impacts at the synapse

SA Bradley, JR Steinert - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Nitric oxide (NO) is an important gasotransmitter molecule that is involved in numerous
physiological processes throughout the nervous system. In addition to its involvement in …

Nitric oxide and mitochondrial function in neurological diseases

M Ghasemi, Y Mayasi, A Hannoun, SM Eslami… - Neuroscience, 2018 - Elsevier
Mitochondria are key cellular organelles that play crucial roles in the energy production and
regulation of cellular metabolism. Accumulating evidence suggests that mitochondrial …

The contribution of an imbalanced redox signalling to neurological and neurodegenerative conditions

JR Steinert, H Amal - Free Radical Biology and Medicine, 2023 - Elsevier
Nitric oxide and other redox active molecules such as oxygen free radicals provide essential
signalling in diverse neuronal functions, but their excess production and insufficient …