Thyroid hormones and cancer: a comprehensive review of preclinical and clinical studies

E Krashin, A Piekiełko-Witkowska, M Ellis… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones take major part in normal growth, development and metabolism. Over a
century of research has supported a relationship between thyroid hormones and the …

[PDF][PDF] Thyroid hormone, thyroid hormone receptors, and cancer: a clinical perspective

LC Moeller, D Führer - Endocr Relat Cancer, 2013 - scholar.archive.org
Thyroid hormones (THs) may play a role in diseases other than hyper-and hypothyroidism.
Several lines of evidence suggest tumor-promoting effects of TH and TH receptors. They are …

Role of thyroid hormones in the neoplastic process: an overview

IM Goemann, M Romitti, ELS Meyer… - Endocrine-related …, 2017 - erc.bioscientifica.com
Thyroid hormones (TH) are critical regulators of several physiological processes, which
include development, differentiation and growth in virtually all tissues. In past decades …

Molecular functions of thyroid hormone signaling in regulation of cancer progression and anti-apoptosis

YC Liu, CT Yeh, KH Lin - International Journal of Molecular Sciences, 2019 - mdpi.com
Several physiological processes, including cellular growth, embryonic development,
differentiation, metabolism and proliferation, are modulated by genomic and nongenomic …

Beyond radioiodine: a review of potential new therapeutic approaches for thyroid cancer

M Braga-Basaria, MD Ringel - The Journal of Clinical …, 2003 - academic.oup.com
One of the greatest challenges in the management of patients with follicular cell-derived
thyroid cancer is the treatment of tumors that progress despite surgery, radioiodine, and T4 …

The changing incidence of thyroid cancer

CM Kitahara, JA Sosa - Nature Reviews Endocrinology, 2016 - nature.com
During the past few decades, the incidence of thyroid cancer has increased substantially in
many countries, including the USA. The rise in incidence seems to be attributable both to the …

Thyroid cancer: pathogenesis and targeted therapy

DA Liebner, MH Shah - Therapeutic advances in …, 2011 - journals.sagepub.com
Therapeutic options for advanced, unresectable radioiodine-resistant thyroid cancers have
historically been limited. Recent progress in understanding the pathogenesis of the various …

Thyroid hormone, cancer, and apoptosis

HY Lin, YT Chin, YCSH Yang, HY Lai… - Comprehensive …, 2011 - Wiley Online Library
Thyroid hormones play important roles in regulating normal metabolism, development, and
growth. They also stimulate cancer cell proliferation. Their metabolic and developmental …

Understanding the ever-changing incidence of thyroid cancer

CM Kitahara, JA Sosa - Nature Reviews Endocrinology, 2020 - nature.com
This Comment article provides a behind-the-scenes perspective and update of our 2016
Review, which discussed possible factors contributing to thyroid cancer incidence trends …

Thyroid dysfunction and cancer incidence: a systematic review and meta-analysis

CM Kitahara, F de Vathaire… - Endocrine-Related …, 2020 - erc.bioscientifica.com
In this study, we aimed to evaluate site-specific cancer risks associated with hyperthyroidism
or hypothyroidism. We performed a systematic review of observational studies reporting …