Nanotechnology for targeted therapy of atherosclerosis

S Hossaini Nasr, X Huang - Frontiers in Pharmacology, 2021 - frontiersin.org
Atherosclerosis is the major cause of heart attack and stroke that are the leading causes of
death in the world. Nanomedicine is a powerful tool that can be engineered to target …

Biomimetic and bioresponsive nanotherapies for inflammatory vascular diseases

G Yang, J Song, J Zhang - Nanomedicine, 2020 - Taylor & Francis
Cardiovascular diseases (CVDs) remain one of the leading causes of death worldwide [1].
Vascular inflammation is an important pathological fundamental of many CVDs, such as …

The effects of particle size, shape, density and flow characteristics on particle margination to vascular walls in cardiovascular diseases

HT Ta, NP Truong, AK Whittaker… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Vascular-targeted drug delivery is a promising approach for the treatment of
atherosclerosis, due to the vast involvement of endothelium in the initiation and growth of …

In vivo evaluation of vascular-targeted spheroidal microparticles for imaging and drug delivery application in atherosclerosis

K Namdee, AJ Thompson, A Golinski, S Mocherla… - Atherosclerosis, 2014 - Elsevier
Objective: Vascular-targeting remains a promising strategy for improving the diagnosis and
treatment of coronary artery disease (CAD) by providing localized delivery of imaging and …

Multifunctional nanoscale strategies for enhancing and monitoring blood vessel regeneration

E Chung, LM Ricles, RS Stowers, SY Nam… - Nano Today, 2012 - Elsevier
Nanomedicine has great potential in biomedical applications, and specifically in
regenerative medicine and vascular tissue engineering. Designing nanometer-sized …

Monocyte-mediated drug delivery systems for the treatment of cardiovascular diseases

G Aizik, E Grad, G Golomb - Drug Delivery And Translational Research, 2018 - Springer
Major advances have been achieved in understanding the mechanisms and risk factors
leading to cardiovascular disorders and consequently developing new therapies. A strong …

[HTML][HTML] Advances in drug delivery to atherosclerosis: Investigating the efficiency of different nanomaterials employed for different type of drugs

B Perera, Y Wu, NT Nguyen, HT Ta - Materials Today Bio, 2023 - Elsevier
Atherosclerosis is the build-up of fatty deposits in the arteries. Atherosclerosis is the main
underlying cause of cardiovascular diseases and the leading cause of global morbidity and …

Multifunctional cell membranes-based nano-carriers for targeted therapies: a review of recent trends and future perspective

M Li, Q Guo, C Zhong, Z Zhang - Drug delivery, 2023 - Taylor & Francis
Nanotechnology has ignited a transformative revolution in disease detection, prevention,
management, and treatment. Central to this paradigm shift is the innovative realm of cell …

Nanoparticle functionalization with platelet membrane enables multifactored biological targeting and detection of atherosclerosis

X Wei, M Ying, D Dehaini, Y Su, AV Kroll, J Zhou… - ACS …, 2018 - ACS Publications
Cardiovascular disease represents one of the major causes of death across the global
population. Atherosclerosis, one of its most common drivers, is characterized by the gradual …

Targeting therapeutics to the vascular wall in atherosclerosis–carrier size matters

P Charoenphol, S Mocherla, D Bouis, K Namdee… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: Vascular-targeted imaging and drug delivery systems are promising for the
treatment of atherosclerosis due to the vast involvement of endothelium in the initiation and …