Effect of pretreatment with statins on ischemic stroke outcomes

MJ Reeves, JW Gargano, Z Luo, AJ Mullard, BS Jacobs… - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Statins reduce the risk of stroke in at-risk populations and may
improve outcomes in patients taking statins before an ischemic stroke (IS). Our objectives …

Rising statin use and effect on ischemic stroke outcome

SS Yoon, J Dambrosia, J Chalela, M Ezzeddine… - BMC medicine, 2004 - Springer
Abstract Background Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors)
have neuroprotective effects in experimental stroke models and are commonly prescribed in …

Association between statin use and short-term outcome based on severity of ischemic stroke: a cohort study

B Song, Y Wang, X Zhao, L Liu, C Wang, A Wang… - PLoS …, 2014 - journals.plos.org
Background Statins reportedly improve clinical outcomes for ischemic stroke patients.
However, it is unclear whether the contribution of statin treatment varies depending on the …

Statin use during ischemic stroke hospitalization is strongly associated with improved poststroke survival

AC Flint, H Kamel, BB Navi, VA Rao, BS Faigeles… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Statins reduce infarct size in animal models of stroke and have
been hypothesized to improve clinical outcomes after ischemic stroke. We examined the …

Use of statins after ischemic stroke in young adults and its association with long-term outcome

MME van Dongen, K Aarnio, N Martinez-Majander… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Knowledge of the use of secondary preventive medication in
young adults is limited. We studied the use of statins and its association with subsequent …

Clinical effectiveness of statin therapy after ischemic stroke: primary results from the statin therapeutic area of the patient-centered research into outcomes stroke …

EC O'Brien, MA Greiner, Y Xian, GC Fonarow… - Circulation, 2015 - Am Heart Assoc
Background—In patients with ischemic stroke, data on the real-world effectiveness of statin
therapy for clinical and patient-centered outcomes are needed to better inform shared …

Does pretreatment with statins improve clinical outcome after stroke? A pilot case-referent study

N Jonsson, K Asplund - Stroke, 2001 - Am Heart Assoc
Background and Purpose—In primary and secondary prevention trials, statins have been
shown to reduce the risk of stroke. In addition to lipid lowering, statins have a number of …

Effect of previous statin therapy on severity and outcome in ischemic stroke patients: a population-based study

C Aboa-Eboulé, C Binquet, A Jacquin, M Hervieu… - Journal of …, 2013 - Springer
Although statin therapy has been shown to be effective in the prevention of ischemic stroke,
its effect on stroke severity and early outcome is still controversial. We aimed to evaluate the …

Impact of early statin therapy in patients with ischemic stroke or transient ischemic attack

PS Chen, CL Cheng, YH Kao Yang… - Acta Neurologica …, 2014 - Wiley Online Library
Background Statin therapy has demonstrated benefits in ischemic stroke patients. However,
little is known about whether the timing of statin initiation affects clinical outcomes. The …

Statin treatment and functional outcome after ischemic stroke: case–control and meta-analysis

A Biffi, WJ Devan, CD Anderson, L Cortellini, KL Furie… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Multiple studies suggest that statin use before acute ischemic
stroke is associated with improved functional outcome. However, available evidence is …