Immune responses against SARS-CoV-2 WT and delta variant in elderly BNT162b2 vaccinees

M Jäger, ST Sonnleitner, S Dichtl, E Lafon… - Frontiers in …, 2022 - frontiersin.org
Background Residents of nursing homes are one of the most vulnerable groups during the
severe acute syndrome coronavirus 2 (SARS-CoV-2) pandemic. The aim of this study was to …

BNT162b2 vaccination elicits strong serological immune responses against SARS-CoV-2 including variants of concern in elderly convalescents

B Jahrsdörfer, D Fabricius, J Scholz, C Ludwig… - Frontiers in …, 2021 - frontiersin.org
Elderly residents of long-term care facilities (LTCFs) have long been underrepresented in
studies on vaccine efficacy, particularly in light of currently emerging variants of concern …

BNT162b2 booster vaccination elicits cross-reactive immunity against SARS-CoV-2 variants B. 1.1. 529 and B. 1.617. 2 in convalescents of all ages

B Jahrsdörfer, M Proffen, J Scholz, J Hägele… - Frontiers in …, 2022 - frontiersin.org
In this prospective observational cohort study we analyzed cellular and serological immune
response parameters against SARS-CoV-2 and current variants of concern (VOC) in 147 …

Effectiveness and waning of protection with the BNT162b2 vaccine against the SARS-CoV-2 Delta variant in immunocompromised individuals

Z Szekanecz, Z Vokó, O Surján, É Rákóczi… - Frontiers in …, 2023 - frontiersin.org
Introduction In Hungary, the HUN-VE 3 study determined the comparative effectiveness of
various primary and booster vaccination strategies during the Delta COVID-19 wave. That …

Humoral response to BNT162b2 vaccine against SARS-CoV-2 variants decays after six months

TJ Lopera, M Chvatal-Medina… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 vaccines have shown very high effectiveness in real-world scenarios.
However, there is compelling evidence for a fast-paced waning of immunity. The increasing …

Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals

YS Goh, A Rouers, SW Fong, NZ Zhuo, PX Hor… - Frontiers in …, 2022 - frontiersin.org
The emergence of new SARS-CoV-2 variants, such as the more transmissible Delta and
Omicron variants, has raised concerns on efficacy of the COVID-19 vaccines. Here, we …

Reduced humoral response 3 months following BNT162b2 vaccination in SARS-CoV-2 uninfected residents of long-term care facilities

M Trigueros, E Pradenas, D Palacín… - Age and …, 2022 - academic.oup.com
Background SARS-CoV-2 vaccination is the most effective strategy to protect older residents
of long-term care facilities (LTCF) against severe COVID-19, but primary vaccine responses …

Impaired functional T-cell response to SARS-CoV-2 after two doses of BNT162b2 mRNA vaccine in older people

J Demaret, B Corroyer-Simovic, EK Alidjinou… - Frontiers in …, 2021 - frontiersin.org
Long-term care facility (LTCF) older residents display physiological alterations of cellular
and humoral immunity that affect vaccine responses. Preliminary reports suggested a low …

Characterization of the humoral immune response to BNT162b2 in elderly residents of long-term care facilities five to seven months after vaccination

M Delbrück, S Hoehl, T Toptan, B Schenk, K Grikscheit… - medrxiv, 2021 - medrxiv.org
The elderly residing in long-term care facilities (LTCFs) are a group at high risk for COVID-
19. Hence, monitoring of the vaccine-based immunity has a pivotal role in identifying …

Age-dependent immune response to the Biontech/Pfizer BNT162b2 coronavirus disease 2019 vaccination

L Müller, M Andrée, W Moskorz, I Drexler… - Clinical Infectious …, 2021 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
has led to the development of various vaccines. Real-life data on immune responses elicited …