A2A adenosine receptor and its modulators: overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and …
G Cristalli, C Lambertucci, G Marucci… - Current …, 2008 - ingentaconnect.com
Since the discovery of the biological effects of adenosine, the development of potent and
selective agonists and antagonists of adenosine receptors has been the subject of medicinal …
selective agonists and antagonists of adenosine receptors has been the subject of medicinal …
Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists
G Cristalli, B Cacciari, D Dal Ben… - ChemMedChem …, 2007 - Wiley Online Library
Although significant progress has been made in the past few decades demonstrating that
adenosine modulates a variety of physiological and pathophysiological processes through …
adenosine modulates a variety of physiological and pathophysiological processes through …
A2A adenosine receptor agonists and their potential therapeutic applications. An update
A Guerrero - Current medicinal chemistry, 2018 - ingentaconnect.com
Background: Adenosine is an endogenous purine nucleoside, which mediates a variety of
important biological processes and diseases, such as vasodilation, inflammation, cancer …
important biological processes and diseases, such as vasodilation, inflammation, cancer …
A2A adenosine receptor antagonists as therapeutic candidates: are they still an interesting challenge?
B Cacciari, G Spalluto… - Mini Reviews in Medicinal …, 2018 - ingentaconnect.com
In the past decades, many efforts were undertaken to develop ligands for the adenosine
receptors, with the purpose to individuate agonists and antagonists affinity and selectivity for …
receptors, with the purpose to individuate agonists and antagonists affinity and selectivity for …
Ligands and therapeutic perspectives of adenosine A2A receptors
Adenosine A2A receptors are members of the G protein-coupled receptor family and
mediate multiple physiological effects of adenosine, both at the central nervous system …
mediate multiple physiological effects of adenosine, both at the central nervous system …
A1 receptors ligands: past, present and future trends
S Schenone, C Brullo, F Musumeci… - Current topics in …, 2010 - ingentaconnect.com
Adenosine is a neuromodulator that interacting with four receptors, A1, A2A, A2B and A3, is
involved in the regulation of several biological functions in different organs and tissues …
involved in the regulation of several biological functions in different organs and tissues …
Adenosine A2A receptor as a potential drug target-current status and future perspectives
OHA Al-Attraqchi, M Attimarad… - Current …, 2019 - ingentaconnect.com
Adenosine receptors (ARs) are a class of G-protein coupled receptors (GPCRs) that are
activated by the endogenous substance adenosine. ARs are classified into 4 subtype …
activated by the endogenous substance adenosine. ARs are classified into 4 subtype …
[图书][B] The adenosine receptors
I am pleased to be able to present this fascinating book, which details our current knowledge
in the adenosine receptor (AR) field. Adenosine, a ubiquitously distributed endogenous …
in the adenosine receptor (AR) field. Adenosine, a ubiquitously distributed endogenous …
Therapeutic potential of A2 and A3 adenosine receptor: a review of novel patented ligands
S Federico, G Spalluto - Expert Opinion on Therapeutic Patents, 2012 - Taylor & Francis
Introduction: Adenosine exerts its effects by interacting with G-protein coupled receptors
(GPCR) namely A1, A2A, A2B and A3, respectively. These are involved in several diseases …
(GPCR) namely A1, A2A, A2B and A3, respectively. These are involved in several diseases …
A2A receptor ligands: past, present and future trends
C Manera, G Saccomanni - Current Topics in Medicinal …, 2010 - ingentaconnect.com
The adenosine A2A receptor is a member of the G protein-coupled receptor family and
mediates multiple physiological effects of adenosine, both at the central nervous system and …
mediates multiple physiological effects of adenosine, both at the central nervous system and …