Since the discovery of the biological effects of adenosine, the development of potent and
selective agonists and antagonists of adenosine receptors has been the subject of medicinal …

Although significant progress has been made in the past few decades demonstrating that
adenosine modulates a variety of physiological and pathophysiological processes through …

Background: Adenosine is an endogenous purine nucleoside, which mediates a variety of
important biological processes and diseases, such as vasodilation, inflammation, cancer …

In the past decades, many efforts were undertaken to develop ligands for the adenosine
receptors, with the purpose to individuate agonists and antagonists affinity and selectivity for …

Adenosine A2A receptors are members of the G protein-coupled receptor family and
mediate multiple physiological effects of adenosine, both at the central nervous system …

Adenosine is a neuromodulator that interacting with four receptors, A1, A2A, A2B and A3, is
involved in the regulation of several biological functions in different organs and tissues …

Adenosine receptors (ARs) are a class of G-protein coupled receptors (GPCRs) that are
activated by the endogenous substance adenosine. ARs are classified into 4 subtype …

I am pleased to be able to present this fascinating book, which details our current knowledge
in the adenosine receptor (AR) field. Adenosine, a ubiquitously distributed endogenous …

Introduction: Adenosine exerts its effects by interacting with G-protein coupled receptors
(GPCR) namely A1, A2A, A2B and A3, respectively. These are involved in several diseases …

The adenosine A2A receptor is a member of the G protein-coupled receptor family and
mediates multiple physiological effects of adenosine, both at the central nervous system and …