Effects of polysaccharides from Gastrodia elata on the immunomodulatory activity and gut microbiota regulation in cyclophosphamide‐treated mice

N Li, D Wang, X Wen, R Chu, J Fan… - Journal of the …, 2023 - Wiley Online Library
BACKGROUND Cyclophosphamide (CTX) is a widely used chemotherapeutic agent for the
treatment of malignant tumors and autoimmune diseases. However, it can cause …

Therapeutic efficacy and underlying mechanisms of Gastrodia elata polysaccharides on dextran sulfate sodium-induced inflammatory bowel disease in mice …

D Xu, Q Wu, W Liu, G Hu, H Meng, J Wang - International Journal of …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic inflammatory gastrointestinal disease, and an
imbalance in the gut microbiota is a critical factor in its development. Gastrodia elata (G …

Polysaccharides From the Roots of Millettia Speciosa Champ Modulate Gut Health and Ameliorate Cyclophosphamide-Induced Intestinal Injury and …

X Chen, W Sun, B Xu, E Wu, Y Cui, K Hao… - Frontiers in …, 2021 - frontiersin.org
Cyclophosphamide (CTX), a common anticancer drug, can cause a variety of side effects
such as immunosuppression and intestinal mucosal injury. Polysaccharides are the major …

Ginger polysaccharides enhance intestinal immunity by modulating gut microbiota in cyclophosphamide-induced immunosuppressed mice

J Liu, J Wang, S Zhou, D Huang, G Qi… - International Journal of …, 2022 - Elsevier
In this study, the immunity-enhancing effect of ginger polysaccharides UGP1 and UGP2 on
CTX-induced immunosuppressed mice was evaluated. The results showed that ginger …

Modulating the gut microbiota is involved in the effect of low-molecular-weight Glycyrrhiza polysaccharide on immune function

W Song, Y Wang, G Li, S Xue, G Zhang, Y Dang… - Gut …, 2023 - Taylor & Francis
ABSTRACT Low molecular weight (6.5 kDa) Glycyrrhiza polysaccharide (GP) exhibits good
immunomodulatory activity, however, the mechanism underlying GP-mediated regulation of …

Bioactive polysaccharides promote gut immunity via different ways

X Wu, X Huang, W Ma, M Li, J Wen, C Chen, L Liu… - Food & Function, 2023 - pubs.rsc.org
Numerous kinds of bioactive polysaccharides are identified as having intestinal
immunomodulatory activity; however, the ways in which the different polysaccharides work …

Water-soluble polysaccharides from Grifola Frondosa fruiting bodies protect against immunosuppression in cyclophosphamide-induced mice via JAK2/STAT3/SOCS …

M Meng, M Guo, C Feng, R Wang, D Cheng… - Food & Function, 2019 - pubs.rsc.org
Grifola Frondosa, the king of mushrooms, is one of the most valued traditional medicines
and has been used as a health food for a long time in China, Japan, and other Asian …

Dendrobium huoshanense polysaccharide regionally regulates intestinal mucosal barrier function and intestinal microbiota in mice

SZ Xie, B Liu, HY Ye, QM Li, LH Pan, XQ Zha, J Liu… - Carbohydrate …, 2019 - Elsevier
The present study investigated the effects of a homogeneous Dendrobium huoshanense
polysaccharide (GXG) on mucosal barrier function and microbiota composition in different …

The investigation of immunomodulatory activities of Gloeostereum incaratum polysaccharides in cyclophosphamide-induced immunosuppression mice

D Wang, Q Li, Y Qu, M Wang… - Experimental and …, 2018 - spandidos-publications.com
Gloeostereum incarnatum, a precious edible mushroom, displays anti‑bacterial and anti‑
inflammatory activities; however, its immunomodulatory effect has not been studied yet. The …

Effects of polysaccharides from Fuzhuan brick tea on immune function and gut microbiota of cyclophosphamide-treated mice

Y Bai, Z Zeng, Z Xie, G Chen, D Chen, Y Sun… - The Journal of …, 2022 - Elsevier
In this study, cyclophosphamide (Cy) was used to treat mice to establish an
immunosuppressant model in mice, and the regulatory effects of polysaccharides from …