OBJECTIVE: To investigate whether the Agouti-related protein (Agrp), the melanocortin
receptor antagonist, alters oxygen consumption, as a measure of energy expenditure …

The melanocortin system plays an important role in the regulation of energy homeostasis.
The Agouti-related protein (AGRP) is a natural antagonist of the action of alpha-melanocyte …

We investigated if agouti-related peptide (AgRP), an endogenous antagonist of
melanocortin receptors (MC3-R and MC4-R), effects energy expenditure in rats. Fragments …

The melanocortin receptor (MC3-R and MC4-R) antagonist, agouti-related protein (AGRP),
is a potent stimulant of food intake. We examined the effect of chronic intracerebroventricular …

Activation of brain melanocortin-4 receptors (MC4-R) by α-melanocyte-stimulating hormone
(MSH) or inhibition by agouti-related protein (AgRP) regulates food intake and energy …

Agouti-related protein (AGRP) is a newly identified orexigenic peptide that acts as an
endogenous antagonist of melanocortin receptors MC3 and MC4. The present study …

Agouti-related protein (Agrp) is present in rat and human hypothalamus and is structurally
related to agouti protein. Over-expression of either of these proteins results in obesity …

Overexpression of agouti-related peptide (AgRP), an endogenous melanocortin (MC) 3 and
4 receptor antagonist (MC3/4-R), causes obesity. Exogenous AgRP-(83—132) increases …

Agouti-related protein (Agrp) is an endogenous melanocortin-4 receptor antagonist
implicated in the regulation of food intake. Effects of Agrp on feeding under varying …

The central melanocortin system plays an important role in the regulation of energy
homeostasis both in rodents and humans, and melanocortin receptors appear to be the core …