Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent

M López‐Lázaro - Molecular nutrition & food research, 2008 - Wiley Online Library
A growing body of research suggests that curcumin, the major active constituent of the
dietary spice turmeric, has potential for the prevention and therapy of cancer. Preclinical …

[PDF][PDF] Anticancer potential of curcumin: preclinical and clinical studies

BB Aggarwal, A Kumar, AC Bharti - Anticancer research, 2003 - curcuminresearch.org
Curcumin (diferuloylmethane) is a polyphenol derived from the plant Curcuma longa,
commonly called turmeric. Extensive research over the last 50 years has indicated this …

Curcumin as an inhibitor of cancer

M Nagabhushan, SV Bhide - Journal of the American College of …, 1992 - Taylor & Francis
Curcumin I (Cur I) and curcumin III (Cur III) are the yellow coloring phenolic compounds
isolated from the spice turmeric. The effect of curcumins on different stages of development …

Latest in vitro and in vivo assay, clinical trials and patents in cancer treatment using curcumin: a literature review

K Doello, R Ortiz, PJ Alvarez, C Melguizo… - Nutrition and …, 2018 - Taylor & Francis
Curcumin, the main active compound of the curcuma root, shows antioxidant, anti-
inflammatory, and antitumor properties which have been demonstrated in preclinical and …

Chemopreventive properties of curcumin

FC Campbell, GP Collett - Future Oncology, 2005 - Taylor & Francis
Inhibition of defined molecular steps of tumorigenesis by natural nontoxic compounds may
be an efficient means to tackle the population cancer burden. Extensive research has …

Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2

C Syng-Ai, AL Kumari, A Khar - Molecular cancer therapeutics, 2004 - AACR
Curcumin, a well-known dietary pigment derived from Curcuma longa, inhibited growth of
several types of malignant cells both in vivo and in vitro. However, its mechanism of action …

Biological effects of curcumin and its role in cancer chemoprevention and therapy

S Singh, A Khar - Anti-Cancer Agents in Medicinal Chemistry …, 2006 - ingentaconnect.com
Curcumin, a natural component of the rhizome of curcuma longa has emerged as one of the
most powerful chemopreventive and anticancer agents. Its biological effects range from …

The golden spice curcumin in cancer: A perspective on finalized clinical trials during the last 10 years

AKK Arslan, E Uzunhisarcıklı, MB Yerer… - Journal of Cancer …, 2022 - journals.lww.com
Curcumin, the key bioactive phytochemical present in turmeric (Curcuma longa L.), is the
most studied natural compound in cancer. Preclinical studies (in vitro and in vitro) and …

Chemopreventive and therapeutic effects of curcumin

A Duvoix, R Blasius, S Delhalle, M Schnekenburger… - Cancer letters, 2005 - Elsevier
Chemoprevention is a promising anti-cancer approach with reduced secondary effects in
comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive …

The multifaceted role of curcumin in cancer prevention and treatment

MK Shanmugam, G Rane, MM Kanchi, F Arfuso… - Molecules, 2015 - mdpi.com
Despite significant advances in treatment modalities over the last decade, neither the
incidence of the disease nor the mortality due to cancer has altered in the last thirty years …