Chronic exposure to low-level cadmium induced zinc-copper dysregulation

S Satarug, M Nishijo, P Ujjin, MR Moore - Journal of Trace Elements in …, 2018 - Elsevier
Background and objectives Exposure to cadmium (Cd) has been associated with aberrant
zinc and copper homeostasis. This study investigated if Cd exposure impairs renal …

The association between renal tubular dysfunction and zinc level in a Chinese population environmentally exposed to cadmium

X Chen, Z Wang, G Zhu, GF Nordberg, X Ding… - Biological Trace Element …, 2018 - Springer
Studies in vivo and in vitro have shown a protective effect of zinc against renal dysfunction
caused by cadmium exposure. However, limited human data is available. In this study, we …

Low serum zinc is associated with elevated risk of cadmium nephrotoxicity

YS Lin, WC Ho, JL Caffrey, B Sonawane - Environmental research, 2014 - Elsevier
Background Despite animal evidence suggests that zinc modulates cadmium nephrotoxicity,
limited human data are available. Objective To test the hypothesis that low serum zinc …

[HTML][HTML] Copper–zinc imbalance induces kidney tubule damage and oxidative stress in a population exposed to chronic environmental cadmium

SY Eom, DH Yim, M Huang, CH Park, GB Kim… - International archives of …, 2020 - Springer
Purpose This cross-sectional study aimed to assess the effect of environmental cadmium
(Cd) exposure and essential metal imbalance on renal tubular damage and oxidative stress …

Changes in zinc and copper homeostasis in human livers and kidneys associated with exposure to environmental cadmium

S Satarug, JR Baker, PE Reilly… - Human & …, 2001 - journals.sagepub.com
This study was undertaken to assess changes in zinc and copper homeostasis in human
tissues that could be attributed to human exposure to environmental cadmium, using …

Zinc and multi-mineral supplementation should mitigate the pathogenic impact of cadmium exposure

MF McCarty - Medical Hypotheses, 2012 - Elsevier
High-level cadmium (Cd) exposure has long been known to induce nephropathy, severe
osteoporosis, and fractures in humans. More recent epidemiology, however, reveals that, in …

Associations between blood cadmium concentration and kidney function in the US population: Impact of sex, diabetes and hypertension

JM Madrigal, AC Ricardo, V Persky, M Turyk - Environmental research, 2019 - Elsevier
Background Exposure to cadmium has been associated with nephropathy and implicated in
the development of diabetes and hypertension. The role of environmental metal exposure …

[HTML][HTML] The risk factors of blood cadmium elevation in chronic kidney disease

KF Tsai, PC Hsu, CT Kung, CT Lee, HL You… - International Journal of …, 2021 - mdpi.com
Low-level cadmium exposure has adverse effects on chronic kidney disease (CKD);
however, the risk factors for elevated blood cadmium levels (BCLs) have not been studied in …

Cadmium & its adverse effects on human health

A Bernard - Indian journal of medical research, 2008 - journals.lww.com
Abstract Cadmium (Cd), a by-product of zinc production, is one of the most toxic elements to
which man can be exposed at work or in the environment. Once absorbed, Cd is efficiently …

[HTML][HTML] Dietary cadmium intake and its effects on kidneys

S Satarug - Toxics, 2018 - mdpi.com
Cadmium (Cd) is a food-chain contaminant that has high rates of soil-to-plant transference.
This phenomenon makes dietary Cd intake unavoidable. Although long-term Cd intake …