Rheumatoid arthritis (RA) clinical trials often include at least 10 measures of disease activity
(eg, tender and swollen joint counts, erythrocyte sedimentation rate, patient pain, grip …

Objective. To develop a set of disease activity measures for use in rheumatoid arthritis (RA)
clinical trials, as well as to recommend specific methods for assessing each outcome …

There is no agreement as to which variable best mirrors disease activity in rheumatoid
arthritis (RA) and no studies have been performed on the validity of disease activity …

The measurement of disease activity in rheumatoid arthritis (RA) reflects the complicated
nature of the disease: elements include the number of tender and swollen joints, pain …

Objective Assessor‐based disease activity measures such as the Disease Activity Score in
28 joints (DAS28), although widely used in rheumatoid arthritis (RA), have high …

In the area of rheumatoid arthritis (RA) clinical trials, there is a continuous process of
developing new—or revising existing—outcome measures. This process may be the result …

Objectives To present the properties of an efficiency measure that may be used to make
statistical comparisons of sensitivities of trial outcome measures. To use this measure to …

Important progress has been reported over the past year on evaluation and standardization
of disease activity variables in rheumatoid arthritis and their relation to outcome measures …

FOR many years disease activity in rheumatoid arthritis (RA) has been measured by an
enormous number of different variables as a single golden standard for measuring disease …

There is no single 'gold standard'quantitative measure to assess and monitor the clinical
status in patients with rheumatoid arthritis (RA). Therefore, a variety of measures have been …