The paradigm of conditioned place preference has been widely used to demonstrate the
rewarding properties of psychomotor stimulants. Such drugs also stimulate locomotor …

Background The expanding set of genomics tools available for inbred mouse strains has
renewed interest in phenotyping larger sets of strains. The present study aims to explore …

Rationale The place conditioning procedure is increasingly used to study relapse in drug
seeking in mice. However, the retention course of drug-induced place preference has not …

The conditioned place preference (CPP) procedure is a popular method used for testing the
rewarding properties of human drugs of abuse. Most CPP studies utilize mammalian …

Rationale Age of initial exposure to addictive substances is inversely proportional to risk of
developing drug dependence. There is debate, however, as to whether intake at a young …

To explore sex differences in reinstatement of conditioned place preference, we subjected
intact male and female Long Evans rats to an extended conditioned place preference (CPP) …

The identification of behavioral traits that could predict an individual's susceptibility to
engage in cocaine addiction is relevant for understanding and preventing this disorder, but …

Only a subgroup of human drug users progress from initial drug taking to drug addiction. The
learned associations between the effects of the drug and the environment in which it is …

The rewarding effect of cocaine as reflected by the development of conditioned place
preference was examined in C57BL/6J and 129/J mice. Cocaine was administered in a …

Rationale: In previous comparisons with C57BL/6J mice, DBA/2J mice have been
characterized as” hyporesponsive” to cocaine's rewarding effect in the conditioned place …