IL-17C/IL-17 receptor E signaling in CD4+ T cells promotes TH17 cell-driven glomerular inflammation
S Krohn, JF Nies, S Kapffer, T Schmidt… - Journal of the …, 2018 - journals.lww.com
The IL-17 cytokine family and the cognate receptors thereof have a unique role in organ-
specific autoimmunity. Most studies have focused on the founding member of the IL-17 …
specific autoimmunity. Most studies have focused on the founding member of the IL-17 …
[HTML][HTML] IL-17 receptor C signaling controls CD4+ Th17 immune responses and tissue injury in immune-mediated kidney diseases
T Schmidt, J Luebbe, C Kilian, JH Riedel… - Journal of the …, 2021 - journals.lww.com
Background IL-17A–producing CD4+ T helper (TH 17) cells play a critical role in
autoimmune and chronic inflammatory diseases, such as crescentic GN. The …
autoimmune and chronic inflammatory diseases, such as crescentic GN. The …
An essential role of interleukin-17 receptor signaling in the development of autoimmune glomerulonephritis
In recent years, proinflammatory cytokines in the nephritic kidney appear to contribute to the
pathogenesis of AGN. The complex inflammatory cytokine network that drives renal …
pathogenesis of AGN. The complex inflammatory cytokine network that drives renal …
IL-17F promotes tissue injury in autoimmune kidney diseases
JH Riedel, HJ Paust, S Krohn, JE Turner… - Journal of the …, 2016 - journals.lww.com
The TH 17 immune response has a central role in the pathogenesis of autoimmune
diseases, implicating the TH 17 master cytokine, IL-17A, as the critical mediator of diseases …
diseases, implicating the TH 17 master cytokine, IL-17A, as the critical mediator of diseases …
Mechanisms and functions of IL-17 signaling in renal autoimmune diseases
T Schmidt, J Luebbe, HJ Paust, U Panzer - Molecular immunology, 2018 - Elsevier
Immune-mediated glomerular diseases (glomerulonephritis) encompass a heterogeneous
collection of diseases that cause inflammation within the glomerulus and other renal …
collection of diseases that cause inflammation within the glomerulus and other renal …
IL-17 in renal immunity and autoimmunity
PS Biswas - The Journal of Immunology, 2018 - journals.aai.org
The kidney is an organ particularly susceptible to damage caused by infections and
autoimmune conditions. Renal inflammation confers protection against microbial infections …
autoimmune conditions. Renal inflammation confers protection against microbial infections …
The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis
HJ Paust, JE Turner, OM Steinmetz… - Journal of the …, 2009 - journals.lww.com
T cells infiltrate the kidney in both human and experimental glomerulonephritis, and several
lines of evidence indicate that T cell-mediated tissue damage plays an important role in the …
lines of evidence indicate that T cell-mediated tissue damage plays an important role in the …
Renal IL-17 expression in human ANCA-associated glomerulonephritis
J Velden, HJ Paust, E Hoxha… - American Journal …, 2012 - journals.physiology.org
Interleukin-17A (IL-17) promotes inflammatory renal tissue damage in mouse models of
crescentic glomerulonephritis, including murine experimental autoimmune anti …
crescentic glomerulonephritis, including murine experimental autoimmune anti …
[HTML][HTML] Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice
D Odobasic, PY Gan, SA Summers, TJ Semple… - The American journal of …, 2011 - Elsevier
T helper (Th) 17 cells might contribute to immune-mediated renal injury. Thus, we sought to
define the time course of IL-17A-induced kidney damage and examined the relation …
define the time course of IL-17A-induced kidney damage and examined the relation …
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN
JE Turner, C Krebs, AP Tittel, HJ Paust… - Journal of the …, 2012 - journals.lww.com
The Th17 immune response appears to contribute to the pathogenesis of human and
experimental crescentic GN, but the cell types that produce IL-17A in the kidney, the …
experimental crescentic GN, but the cell types that produce IL-17A in the kidney, the …