One hallmark of psychiatric conditions is the vast continuum of individual differences in
susceptibility vs. resilience resulting from the interaction of genetic and environmental …

Environmental enrichment during development produces a host of neurobehavioral effects
in preclinical models. Early work demonstrated that enrichment enhances learning of a …

Life experiences, especially during critical periods of maturation, such as adolescence, can
dramatically affect vulnerability to diseases at adulthood. Early exposure to positive …

Environmental stimulation throughout development adjusts the neurobehavioral systems
involved in learning, memory and defensive responses. Environment-mediated phenotypic …

Environmental conditions can dramatically influence the behavioral and neurochemical
effects of drugs of abuse. For example, stress increases the reinforcing effects of drugs and …

The subgranular zone of the adult hippocampal dentate gyrus contains a pool of neural stem
cells that continuously divide and differentiate into functional granule cells. It has been …

It is known that negative environmental conditions increase vulnerability to drugs, whereas
little is known on whether positive environmental conditions such as enriched environments …

Stress inoculation entails intermittent exposure to mildly stressful situations that present
opportunities to learn, practice and improve coping in the context of exposure …

Environmental enrichment (EE) has been shown to have powerful beneficial effects on a
variety of physiological and pathological processes. Accumulating evidence indicates that …

Chronic stress is one of the predominant environmental risk factors for a number of
psychiatric disorders, particularly for major depression. Different hypotheses have been …