Osteosarcoma (OS) is the most common human primary malignant bone tumor in children
and young adults with poor prognosis because of their high metastatic potential …

Osteosarcoma is rare but is the most common bone tumor. Diagnostic tools such as
magnetic resonance imaging development of chemotherapeutic agents have increased the …

Purpose An intense vascularization of primary tumor mass is associated with a fatal outcome
in various types of invasive solid tumors. Interleukin 17 (IL-17), a CD4+ T-cell-derived …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide.
Recent data suggested that IL-17 might be a pivotal cytokine involved in tumor progression …

In carcinogenesis, inflammasomes may play contradictory roles through facilitating anti-
tumor immunity or inducing oncogenic factors. Their function in cancer remains poorly …

IL-17RB, a member of the IL-17 receptor family that can be activated by IL-17B, has been
proved to be involved in inflammatory diseases and cancers. However, the function of IL …

Background The tumor microenvironment plays a key role in non-small cell lung cancer
(NSCLC) development and also influences the effective response to immunotherapy. The …

Abstract Interleukin-17 receptor (IL-17RA) is essential for proinflammatory cytokine IL-17-
mediated pathogenesis of various tumors. IL-17RA is upregulated by some proinflammatory …

Abstract Interleukin-17A (IL-17A) plays a significant role in many inflammatory diseases and
cancers. The aim of this study is to investigate the effect of IL-17A on the invasiveness of …

The present study is to investigate the effect and mechanism of action of interleukin (IL)-17A
and its receptor IL-17RA on non-small cell lung cancer (NSCLC). A total of 139 NSCLC …