Adenosine to inosine (A-to-I) RNA editing, catalyzed by the ADAR enzyme family, acts on
dsRNA structures within pre-mRNA molecules. Editing of the coding part of the mRNA may …

Adenosine-to-inosine (A-to-I) editing is a post-transcriptional modification of RNA which
changes its sequence, coding potential and secondary structure. Catalysed by the …

A-to-I editing is an adenosine-to-inosine modification of mRNA particularly widespread in
the human brain, where it affects thousands of genes. A growing body of evidence suggests …

Adenosine to inosine (A-to-I) RNA editing is a base recoding process within precursor
messenger RNA, catalyzed by members of the adenosine deaminase acting on RNA …

Adenosine to inosine deamination of RNA is widespread in metazoa. Inosines are
recognized as guanosines and, therefore, this RNA-editing can influence the coding …

Adenosine to inosine (A> I) RNA editing, which is catalyzed by the ADAR family of proteins,
is one of the fundamental mechanisms by which transcriptomic diversity is generated …

Abstract Adenosine-to-inosine (A-to-I) RNA editing, in which genomically encoded
adenosine is changed to inosine in RNA, is catalyzed by adenosine deaminase acting on …

RNA editing is an alteration in the primary nucleotide sequences resulting from a chemical
change in the base. RNA editing is observed in eukaryotic mRNA, transfer RNA, ribosomal …

Background RNA-editing is a tightly regulated, and essential cellular process for a properly
functioning brain. Dysfunction of A-to-I RNA editing can have catastrophic effects …

RNA editing is a feature of RNA maturation resulting in the formation of transcripts whose
sequence differs from the genome template. Brain RNA editing may be altered in …