Assessing ACE2 expression patterns in lung tissues in the pathogenesis of COVID-19

G Li, X He, L Zhang, Q Ran, J Wang, A Xiong… - Journal of …, 2020 - Elsevier
It has been reported that SARS-CoV-2 may use ACE2 as a receptor to gain entry into human
cells, in a way similar to that of SARS-CoV. Analyzing the distribution and expression level of …

Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues

MY Li, L Li, Y Zhang, XS Wang - Infectious diseases of poverty, 2020 - mednexus.org
Background: Since its discovery in December 2019, severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has infected more than 2 180 000 people worldwide and has …

[PDF][PDF] Susceptibility analysis of COVID-19 in smokers based on ACE2

J Wang, Q Luo, R Chen, T Chen, J Li - 2020 - pdfs.semanticscholar.org
Background: Cigarette smoking (CS) is a global public health problem and a high-risk factor
for various diseases. In December 2019, a novel coronavirus (COVID-19) was identified in …

Expression of ACE2, the SARS-CoV-2 receptor, in lung tissue of patients with type 2 diabetes

SRA Wijnant, M Jacobs, HP Van Eeckhoutte… - Diabetes, 2020 - Am Diabetes Assoc
Increased expression of pulmonary ACE2, the SARS-CoV-2 receptor, could contribute to
increased infectivity of COVID-19 in patients with diabetes, but ACE2 expression has not …

Expression of ACE2 in airways: Implication for COVID‐19 risk and disease management in patients with chronic inflammatory respiratory diseases

Y Yao, H Wang, Z Liu - Clinical & Experimental Allergy, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has been a rising international cause of …

[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy

PK Datta, F Liu, T Fischer, J Rappaport, X Qin - Theranostics, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …

Manipulation of ACE2 expression in COVID-19

F Chaudhry, S Lavandero, X Xie, B Sabharwal… - Open …, 2020 - openheart.bmj.com
SARS-CoV-2 is the virus responsible for the ongoing COVID-19 outbreak. The virus uses
ACE2 receptor for viral entry. ACE2 is part of the counter-regulatory renin-angiotensin …

[HTML][HTML] A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells

Y Wang, Y Wang, W Luo, L Huang, J Xiao… - … journal of medical …, 2020 - ncbi.nlm.nih.gov
The outbreak of pneumonia caused by SARS-CoV-2 posed a great threat to global human
health, which urgently requires us to understand comprehensively the mechanism of SARS …

Systematic profiling of ACE2 expression in diverse physiological and pathological conditions for COVID‐19/SARS‐CoV‐2

Y Li, Q Xu, L Ma, D Wu, J Gao… - Journal of cellular and …, 2020 - Wiley Online Library
Recent retrospective studies of severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2) disease (COVID‐19) revealed that the patients with common comorbidities of …

Expression of ACE2, soluble ACE2, angiotensin I, angiotensin II and angiotensin-(1-7) is modulated in COVID-19 patients

IO Osman, C Melenotte, P Brouqui, M Million… - Frontiers in …, 2021 - frontiersin.org
The etiological agent of COVID-19 SARS-CoV-2, is primarily a pulmonary-tropic
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …