Developmental disorders of the hypothalamus and pituitary gland associated with congenital hypopituitarism

A Mehta, MT Dattani - Best Practice & Research Clinical Endocrinology & …, 2008 - Elsevier
The pituitary gland is a complex organ secreting six hormones from five different cell types. It
is the end product of a carefully orchestrated pattern of expression of signalling molecules …

Genetic forms of hypopituitarism and their manifestation in the neonatal period

KS Alatzoglou, MT Dattani - Early human development, 2009 - Elsevier
The anterior pituitary gland is a central regulator of growth, reproduction and homeostasis.
The development of the pituitary gland depends on the sequential temporal and spatial …

The role of transcription factors implicated in anterior pituitary development in the aetiology of congenital hypopituitarism

D Kelberman, MT Dattani - Annals of medicine, 2006 - Taylor & Francis
The anterior pituitary gland is a central regulator of growth, reproduction and homeostasis,
and is the end‐product of a carefully orchestrated pattern of expression of signalling …

Hypothalamic and pituitary development: novel insights into the aetiology

D Kelberman, MT Dattani - European journal of endocrinology, 2007 - academic.oup.com
The anterior pituitary gland is a central regulator of growth, reproduction and homeostasis,
and is the end-product of a carefully orchestrated pattern of expression of signalling …

[HTML][HTML] Congenital hypopituitarism: various genes, various phenotypes

M Xatzipsalti, A Voutetakis… - Hormone and …, 2019 - thieme-connect.com
The ontogenesis and development of the pituitary gland is a highly complex process that
depends on a cascade of transcription factors and signaling molecules. Spontaneous …

The molecular basis of hypopituitarism

CJ Romero, S Nesi-França, S Radovick - Trends in Endocrinology & …, 2009 - cell.com
Hypopituitarism is defined as the deficiency of one or more of the hormones secreted by the
pituitary gland. Several developmental factors necessary for pituitary embryogenesis and …

Role of transcription factors in midline central nervous system and pituitary defects

D Kelberman, MT Dattani - Endocrine Involvement in …, 2009 - books.google.com
The anterior pituitary gland is a central regulator of growth, reproduction and homeostasis,
and is the end-product of a carefully orchestrated pattern of expression of signalling …

Hypopituitarism oddities: congenital causes

D Kelberman, MT Dattani - Hormone research, 2007 - karger.com
Background: The last 15 years have witnessed an explosion in our knowledge of
hypothalamo-pituitary development, acquired mainly from naturally-occurring and …

[HTML][HTML] Congenital hypopituitarism during the neonatal period: epidemiology, pathogenesis, therapeutic options, and outcome

L Bosch i Ara, H Katugampola, MT Dattani - Frontiers in pediatrics, 2021 - frontiersin.org
Introduction: Congenital hypopituitarism (CH) is characterized by a deficiency of one or more
pituitary hormones. The pituitary gland is a central regulator of growth, metabolism, and …

The molecular basis of congenital hypopituitarism and related disorders

LC Gregory, MT Dattani - The Journal of Clinical Endocrinology …, 2020 - academic.oup.com
Context Congenital hypopituitarism (CH) is characterized by the presence of deficiencies in
one or more of the 6 anterior pituitary (AP) hormones secreted from the 5 different …