From the pathogenic point of view, penile cancers may be grouped in human papillomavirus-
related and unrelated tumors, each one of them with distinctive morphologic features. The …

Background One third to one half of penile squamous cell carcinomas (SCCs) are related to
human papillomavirus (HPV) infection. Viral detection is usually carried out by polymerase …

There are few pathologic or molecular studies of penile precancerous lesions, and the
majority refers to lesions associated with invasive carcinomas. Penile Intraepithelial …

Approximately 50% of penile squamous cell carcinomas (SCC) are associated with high-risk
human papillomavirus (HR-HPV) infection. We evaluated the correlation of p16 INK4a …

Several classification schemes for penile precancerous lesions have been proposed, but
none of them seems to correlate with the current understanding of penile cancer …

Background Up to 50% of penile squamous cell carcinomas (pSCC) develop in the context
of high-risk human papillomavirus (HR-HPV) infection. Most of these tumours have been …

BACKGROUND: Penile squamous cell carcinomas (SCC) arise either through transforming
infections with human papillomavirus (HPV) or independent of HPV, often in the background …

We evaluated p16INK4a as a reliable option to detect human papilloma virus (HPV) DNA in
penile tumor specimens. Formalin-fixed paraffin embedded samples of 26 patients with …

Background Infection with human papillomavirus (HPV) is reported to be present in 30–50%
of penile cancer cases. The immunohistochemical test for p16INK4a is used as an indicator …

PURPOSE: We assessed the prognostic role of p16INK4a expression in penile cancer with
respect to cancer specific survival. MATERIALS AND METHODS: Based on a multi …