G-quadruplexes (G4) are secondary structures formed by guanine-rich nucleic acid
sequences and shown to exist in living cells where they participate in regulation of gene …

The initial aim of this work was to elucidate the mutual influence of different single-stranded
segments (loops and caps) on the thermodynamic stability of RNA G-quadruplexes. To this …

Cations are known to mediate diverse interactions in nucleic acids duplexes but they are
critical in the arrangement of four-stranded structures. Here, we use all-atom molecular …

The lengths of G-tracts and their connecting loop sequences determine G-quadruplex
folding and stability. Complete understanding of the sequence–structure relationships …

G-Quadruplexes (G4s) are ubiquitous nucleic acid folding motifs that exhibit structural
diversity that is dependent on cationic conditions. In this work, we exploit temperature …

The self-assembly and stability of DNA G-quadruplexes (GQs) are affected by the intrinsic
stability of different GpG base steps embedded in their G-quartet stems. We have carried out …

G-quadruplexes (GQs) are key noncanonical DNA and RNA architectures stabilized by
desolvated monovalent cations present in their central channels. We analyze extended …

The guanine quadruplexes are DNA/RNA guanine-rich sequences assembled into four-
stranded helical structures having important roles in gene regulation and chromosome …

G-quadruplex is a noncanonical yet crucial secondary structure of nucleic acids, which has
proven its importance in cell aging, anticancer therapies, gene expression, and genome …

Single-stranded guanine-rich sequences fold into compact G-quadruplexes. Although G-
triplexes have been proposed and demonstrated as intermediates in the folding of G …