The role of interleukin‐17 in mouse models of atopic dermatitis and contact dermatitis

WI Heo, KE Lee, JY Hong, MN Kim… - Clinical and …, 2015 - academic.oup.com
Background Atopic dermatitis (AD) and contact dermatitis (CD) are both T cell‐mediated
eczematous disorders. Interleukin (IL)‐17, expressed by T helper (Th) 17 cells, is involved in …

[HTML][HTML] MicroRNA‑146a as a potential regulator involved in the pathogenesis of atopic dermatitis

F Yan, W Meng, S Ye, X Zhang… - Molecular …, 2019 - spandidos-publications.com
Previous studies have demonstrated that microRNA (miR)‑146a is involved in the
inflammatory response of atopic dermatitis (AD). The aim of the present study was to …

[PDF][PDF] Optimization of cytokine milieu to reproduce atopic dermatitis-related gene expression in HaCaT keratinocyte cell line

HJ Kim, J Baek, JR Lee, JY Roh, YJ Jung - Immune Network, 2018 - synapse.koreamed.org
Although atopic dermatitis (AD) is characterized by cytokine production predominantly
mediated by T helper (Th) 2 cells, AD pathogenesis also involves innate immune and Th1 …

Serum interleukin‐9 levels are associated with clinical severity in children with atopic dermatitis

G Ciprandi, M De Amici, V Giunta… - Pediatric …, 2013 - Wiley Online Library
Atopic dermatitis (AD) is an inflammatory disorder of the skin characterized by impaired
immune response. Th9 cells are a sub‐population of T cells that release interleukin (IL)‐9 …

[HTML][HTML] Expression of helper and regulatory T cells in atopic dermatitis: a meta-analysis

D Zhang, F Hao, T Qian, H Cheng - Frontiers in Pediatrics, 2022 - frontiersin.org
Background Atopic dermatitis (AD) is a common inflammatory skin disease, with the
incidence peaks in infancy. A meta-analysis was performed to assess the levels of T helper …

IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions

H Konishi, H Tsutsui, T Murakami… - Proceedings of the …, 2002 - National Acad Sciences
Atopic dermatitis (AD) is a pruritic inflammatory skin disease. Because IL-18 directly
stimulates T cells and mast cells to release AD-associated molecules, Th2 cytokines, and …

Different lymphocyte markers and cytokine expression in peripheral blood mononuclear cells in children with acute atopic dermatitis

C Antunez, MJ Torres, JL Corzo, RR Pena… - Allergologia et …, 2004 - Elsevier
BACKGROUND: The pathogenesis of atopic dermatitis (AD) is still not completely
understood. AD is characterized by the presence of clinical symptoms of both IgE antibody …

Altered cytokine production in atopic dermatitis: a preliminary study

M KNAPIK, M FRIERI - Pediatric Asthma Allergy & Immunology, 1993 - liebertpub.com
Infiltrating lymphocytes in skin lesions from patients with atopic dermatitis are capable of
secreting a variety of interleukins (IL) that may promote IgE synthesis, IL-4, or decrease …

[HTML][HTML] Interplay of cytokines in the pathophysiology of atopic dermatitis: insights from Murin models and human

Y Yamamura, C Nakashima, A Otsuka - Frontiers in Medicine, 2024 - frontiersin.org
The pathogenesis of atopic dermatitis (AD) is understood to be crucially influenced by three
main factors: dysregulation of the immune response, barrier dysfunction, and pruritus. In the …

[HTML][HTML] Th2 cytokines and atopic dermatitis

EB Brandt, U Sivaprasad - Journal of clinical & cellular immunology, 2011 - ncbi.nlm.nih.gov
Atopic dermatitis (AD), a chronic relapsing inflammatory skin disease, is increasing in
prevalence around the world. Intensive research is ongoing to understand the mechanisms …