[HTML][HTML] Non-atopic neonatal thymic innate lymphoid cell subsets (ILC1, ILC2, and ILC3) identification and the modulatory effect of igG from dermatophagoides …
TR de Sousa, FR Sgnotto, BO Fagundes… - Frontiers in …, 2021 - frontiersin.org
Innate lymphoid cells (ILCs) are classified into distinct subsets termed ILC1, ILC2, and ILC3
cells. The existing literature lacks evidence identifying ILCs and their subsets in the human …
cells. The existing literature lacks evidence identifying ILCs and their subsets in the human …
Combining gene expression microarray-and cluster analysis with sequence-based predictions to identify regulators of IL-13 in allergy
S Bruhn, M Katzenellenbogen, M Gustafsson, A Krönke… - Cytokine, 2012 - Elsevier
The Th2 cytokine IL-13 plays a key role in allergy, by regulating IgE, airway hyper secretion,
eosinophils and mast cells. In this study, we aimed to identify novel transcription factors …
eosinophils and mast cells. In this study, we aimed to identify novel transcription factors …
IL-4 up-regulates epidermal chemotactic, angiogenic, and pro-inflammatory genes and down-regulates antimicrobial genes in vivo and in vitro: relevant in the …
L Bao, VY Shi, LS Chan - Cytokine, 2013 - Elsevier
Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Although the
pathogenesis of AD is not fully understood, we and others have shown that IL-4 plays a key …
pathogenesis of AD is not fully understood, we and others have shown that IL-4 plays a key …
[HTML][HTML] RNA-Seq identifies marked Th17 cell activation and altered CFTR expression in different atopic dermatitis subtypes in Chinese Han populations
X Tian, B Liu, L Chen, Y Xie, J Liang, Y Yang… - Frontiers in …, 2021 - frontiersin.org
Background Patients with atopic dermatitis (AD) exhibit phenotypic variability in ethnicity and
IgE status. In addition, some patients develop other allergic conditions, such as allergic …
IgE status. In addition, some patients develop other allergic conditions, such as allergic …
Transgenic mice which overproduce Th2 cytokines develop spontaneous atopic dermatitis and asthma
GR Lee, RA Flavell - International immunology, 2004 - academic.oup.com
We have investigated the role of Th2 cytokines in the development of atopic diseases using
transgenic mice carrying large genomic segments containing IL4, IL13 and IL5 genes and …
transgenic mice carrying large genomic segments containing IL4, IL13 and IL5 genes and …
Impairment of T-regulatory cells in cord blood of atopic mothers
B Schaub, J Liu, S Höppler, S Haug, C Sattler… - Journal of allergy and …, 2008 - Elsevier
BACKGROUND: Maternal atopy is a strong predictor for the development of childhood
allergic diseases. The underlying mechanisms are ill defined, yet regulatory T (Treg) and …
allergic diseases. The underlying mechanisms are ill defined, yet regulatory T (Treg) and …
Molecular biology of atopic dermatitis
Z Mu, Y Zhao, X Liu, C Chang, J Zhang - Clinical reviews in allergy & …, 2014 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin disease with specific genetic and
immunological mechanisms. The rapid development of new techniques in molecular biology …
immunological mechanisms. The rapid development of new techniques in molecular biology …
[HTML][HTML] IL-17A as an inducer for Th2 immune responses in murine atopic dermatitis models
S Nakajima, A Kitoh, G Egawa, Y Natsuaki… - Journal of Investigative …, 2014 - Elsevier
Atopic dermatitis (AD) is generally regarded as a type 2 helper T (Th2)-mediated
inflammatory skin disease. Although the number of IL-17A-producing cells is increased in …
inflammatory skin disease. Although the number of IL-17A-producing cells is increased in …
IL-31–generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin
T Hashimoto, H Yokozeki, H Karasuyama… - Journal of Allergy and …, 2023 - Elsevier
Background IL-31 is a type 2 cytokine involved in the itch sensation in atopic dermatitis (AD).
The cellular origins of IL-31 are generally considered to be TH 2 cells. Macrophages have …
The cellular origins of IL-31 are generally considered to be TH 2 cells. Macrophages have …
In vivo expression of cytokine receptor mRNA in atopic dermatitis
RA Taha, DYM Leung, O Ghaffar… - Journal of allergy and …, 1998 - Elsevier
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease with
immunopathologic features that vary depending on the duration of the lesion. Acute lesions …
immunopathologic features that vary depending on the duration of the lesion. Acute lesions …