Transspinal stimulation decreases corticospinal excitability and alters the function of spinal locomotor networks

TS Pulverenti, MA Islam, O Alsalman… - Journal of …, 2019 - journals.physiology.org
Locomotion requires the continuous integration of descending motor commands and
sensory inputs from the legs by spinal central pattern generator circuits. Modulation of spinal …

Transpinal and transcortical stimulation alter corticospinal excitability and increase spinal output

M Knikou - PLoS One, 2014 - journals.plos.org
The objective of this study was to assess changes in corticospinal excitability and spinal
output following noninvasive transpinal and transcortical stimulation in humans. The size of …

Interactions between arm and leg neuronal circuits following paired cervical and lumbosacral transspinal stimulation in healthy humans

AM Sayed Ahmad, A Skiadopoulos… - Experimental Brain …, 2024 - Springer
Transspinal (or transcutaneous spinal cord) stimulation is a promising noninvasive method
that may strengthen the intrinsic spinal neural connectivity in neurological disorders. In this …

Transspinal stimulation downregulates activity of flexor locomotor networks during walking in humans

M Zaaya, TS Pulverenti, MA Islam, M Knikou - Journal of Electromyography …, 2020 - Elsevier
The objective of this study was to establish the effects of transspinal stimulation on short-
latency tibialis anterior (TA) flexion reflex during walking in healthy humans. Single pulse …

Voluntary modulation of evoked responses generated by epidural and transcutaneous spinal stimulation in humans with spinal cord injury

JS Calvert, ML Gill, MB Linde, DD Veith… - Journal of clinical …, 2021 - mdpi.com
Transcutaneous (TSS) and epidural spinal stimulation (ESS) are electrophysiological
techniques that have been used to investigate the interactions between exogenous …

Transspinal direct current stimulation produces persistent plasticity in human motor pathways

LM Murray, B Tahayori, M Knikou - Scientific reports, 2018 - nature.com
The spinal cord is an integration center for descending, ascending, and segmental neural
signals. Noninvasive transspinal stimulation may thus constitute an effective method for …

Initiation and modulation of locomotor circuitry output with multisite transcutaneous electrical stimulation of the spinal cord in noninjured humans

Y Gerasimenko, R Gorodnichev… - Journal of …, 2015 - journals.physiology.org
The mammalian lumbar spinal cord has the capability to generate locomotor activity in the
absence of input from the brain. Previously, we reported that transcutaneous electrical …

Preferential activation of spinal sensorimotor networks via lateralized transcutaneous spinal stimulation in neurologically intact humans

JS Calvert, GA Manson, PJ Grahn… - Journal of …, 2019 - journals.physiology.org
Transcutaneous spinal stimulation (TSS), a noninvasive technique to modulate sensorimotor
circuitry within the spinal cord, has been shown to enable a wide range of functions that …

The immediate and short-term effects of transcutaneous spinal cord stimulation and peripheral nerve stimulation on corticospinal excitability

Y Al'joboori, R Hannah, F Lenham, P Borgas… - Frontiers in …, 2021 - frontiersin.org
Rehabilitative interventions involving electrical stimulation show promise for neuroplastic
recovery in people living with Spinal Cord Injury (SCI). However, the understanding of how …

Characterization of interlimb interaction via transcutaneous spinal stimulation of cervical and lumbar spinal enlargements

DA Atkinson, AG Steele, GA Manson… - Journal of …, 2022 - journals.physiology.org
The use of transcutaneous electrical spinal stimulation (TSS) to modulate sensorimotor
networks after neurological insult has garnered much attention from both researchers and …