RAGE regulation and signaling in inflammation and beyond

K Kierdorf, G Fritz - Journal of leukocyte biology, 2013 - academic.oup.com
ABSTRACT RAGE is a key molecule in the onset and sustainment of the inflammatory
response. New studies indicate that RAGE might represent a new link between the innate …

RAGE and its ligands: from pathogenesis to therapeutics

N Jangde, R Ray, V Rai - Critical reviews in biochemistry and …, 2020 - Taylor & Francis
Receptor for advanced glycation end products (RAGE) is an immunoglobulin-like receptor
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …

[PDF][PDF] RAGE on the Toll Road

L Lin - Cell Mol Immunol, 2006 - cmi.ustc.edu.cn
Mammalian Toll-like receptors (TLRs) are cellular pattern-recognizing receptors (PRRs) that
recognize the molecular patterns of pathogens. After engaging the pathogenic patterned …

RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts

R Ramasamy, SF Yan… - Journal of leukocyte …, 2009 - academic.oup.com
RAGE may be a biomarker and/or target for therapeutic intervention in chronic disease such
as diabetes, inflammation, neurodegeneration, and tumors. The RAGE binds multiple ligand …

The receptor RAGE: Bridging inflammation and cancer

A Riehl, J Németh, P Angel, J Hess - Cell Communication and Signaling, 2009 - Springer
The receptor for advanced glycation end products (RAGE) is a single transmembrane
receptor of the immunoglobulin superfamily that is mainly expressed on immune cells …

RAGE-mediated cell signaling

A Rouhiainen, J Kuja-Panula, S Tumova… - Calcium-binding proteins …, 2013 - Springer
RAGE (receptor for advanced glycation end products) is a multi-ligand receptor that belongs
to the immunoglobulin superfamily of transmembrane proteins. RAGE binds AGEs …

[HTML][HTML] RAGE signaling in inflammation and arterial aging

L Lin, S Park, EG Lakatta - Frontiers in bioscience: a journal and …, 2009 - ncbi.nlm.nih.gov
The receptor for advanced glycation end products (RAGE) is a pattern recognition receptor
(PRR) that interacts with diverse endogenous ligands. Ligation of RAGE triggers a series of …

[PDF][PDF] RAGE and cardiovascular disease

SPSJY Hyun, J Shim - Front. Biosci, 2011 - article.imrpress.com
[Frontiers in Bioscience 16, 486-497, January 1, 2011] 486 RAGE and cardiovascular disease
Sungha Park1 Se-Jung Yoon3 Hyun-Jin T Page 1 [Frontiers in Bioscience 16, 486-497, January …

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

AM Schmidt, S Du Yan, SF Yan… - The Journal of clinical …, 2001 - Am Soc Clin Investig
AGEs Tumor biology Amphoterin albumin prepared in vitro (7). Its extracellular domain
consists of three immunoglobulin-like regions, one “V”-type followed by two “C”-type (8) …

RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation

LJ Sparvero, D Asafu-Adjei, R Kang, D Tang… - Journal of translational …, 2009 - Springer
Abstract The Receptor for Advanced Glycation Endproducts [RAGE] is an evolutionarily
recent member of the immunoglobulin super-family, encoded in the Class III region of the …