DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples

SE Jung, SM Lim, SR Hong, EH Lee, KJ Shin… - Forensic Science …, 2019 - Elsevier
Many studies have reported age-associated DNA methylation changes and age-predictive
models in various tissues and body fluids. Although age-associated DNA methylation …

DNA methylation age estimation in blood samples of living and deceased individuals using a multiplex SNaPshot assay

HC Dias, C Cordeiro, J Pereira, C Pinto, FC Real… - Forensic science …, 2020 - Elsevier
Many studies in the forensic field have reported that analysis of DNA methylation is the most
reliable method of predicting age. In a previous study, 5 CpG sites located in ELOVL2, FHL2 …

Development of a forensically useful age prediction method based on DNA methylation analysis

R Zbieć-Piekarska, M Spólnicka, T Kupiec… - Forensic Science …, 2015 - Elsevier
Forensic DNA phenotyping needs to be supplemented with age prediction to become a
relevant source of information on human appearance. Recent progress in analysis of the …

Age estimation based on DNA methylation using blood samples from deceased individuals

H Correia Dias, C Cordeiro… - Journal of forensic …, 2020 - Wiley Online Library
Age estimation using DNA methylation levels has been widely investigated in recent years
because of its potential application in forensic genetics. The main aim of this study was to …

[HTML][HTML] DNA methylation-based age prediction from various tissues and body fluids

SE Jung, KJ Shin, HY Lee - BMB reports, 2017 - ncbi.nlm.nih.gov
Aging is a natural and gradual process in human life. It is influenced by heredity,
environment, lifestyle, and disease. DNA methylation varies with age, and the ability to …

[HTML][HTML] Chronological age prediction based on DNA methylation: massive parallel sequencing and random forest regression

J Naue, HCJ Hoefsloot, ORF Mook… - Forensic science …, 2017 - Elsevier
The use of DNA methylation (DNAm) to obtain additional information in forensic
investigations showed to be a promising and increasing field of interest. Prediction of the …

DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers

SR Hong, SE Jung, EH Lee, KJ Shin, WI Yang… - Forensic Science …, 2017 - Elsevier
DNA methylation is currently one of the most promising age-predictive biomarkers. Many
studies have reported DNA methylation-based age predictive models, but most of these are …

Examination of DNA methylation status of the ELOVL2 marker may be useful for human age prediction in forensic science

R Zbieć-Piekarska, M Spólnicka, T Kupiec… - Forensic Science …, 2015 - Elsevier
Age estimation in forensic investigations may complement the prediction of externally visible
characteristics and the inference of biogeographical ancestry, thus allowing a better …

[HTML][HTML] Development of the VISAGE enhanced tool and statistical models for epigenetic age estimation in blood, buccal cells and bones

A Woźniak, A Heidegger, D Piniewska-Róg… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
DNA methylation is known as a biomarker for age with applications in forensics. Here we
describe the VISAGE (VISible Attributes through GEnomics) Consortium's enhanced tool for …

DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups

M Spólnicka, E Pośpiech, B Pepłońska… - International journal of …, 2018 - Springer
Improving accuracy of the available predictive DNA methods is important for their wider use
in routine forensic work. Information on age in the process of identification of an unknown …