GRHL2 acts as an anti-oncogene in bladder cancer by regulating ZEB1 in epithelial-mesenchymal transition (EMT) process
J Shen, X Lv, L Zhang - OncoTargets and therapy, 2020 - Taylor & Francis
Purpose GRHL2 played important roles in different cancers. In this study, we aimed to
investigate the roles of GRHL2 in bladder cancer. Methods The immunohistochemistry …
investigate the roles of GRHL2 in bladder cancer. Methods The immunohistochemistry …
Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1
Y Quan, R Jin, A Huang, H Zhao, B Feng… - Cancer biology & …, 2014 - Taylor & Francis
Previous reports have associated GRHL2 with tumor progression. However, the biological
role of GRHL2 in human colorectal cancer (CRC) has not been explored. We examined the …
role of GRHL2 in human colorectal cancer (CRC) has not been explored. We examined the …
GRHL2 inhibits colorectal cancer progression and metastasis via oppressing epithelial-mesenchymal transition
Z Yang, D Wu, Y Chen, Z Min, Y Quan - Cancer biology & therapy, 2019 - Taylor & Francis
Our previous study has demonstrated that knockdown of Grainyhead-like 2 (GRHL2) in
colorectal cancer (CRC) cells inhibited cell proliferation by targeting ZEB1. This study aimed …
colorectal cancer (CRC) cells inhibited cell proliferation by targeting ZEB1. This study aimed …
[HTML][HTML] GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer
X Pan, R Zhang, C Xie, M Gan, S Yao… - American journal of …, 2017 - ncbi.nlm.nih.gov
The transcription factor, Grainyhead-like 2 (GRHL2), is involved in wound healing,
epidermal integrity, and epithelial-to-mesenchymal transition (EMT) in various biological …
epidermal integrity, and epithelial-to-mesenchymal transition (EMT) in various biological …
Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer
J Xiang, X Fu, W Ran, Z Wang - Oncogenesis, 2017 - nature.com
Metastasis is one of the typical features of malignancy that significantly increases cancer-
related mortality. Recent studies have shown that epithelial–mesenchymal transition (EMT) …
related mortality. Recent studies have shown that epithelial–mesenchymal transition (EMT) …
GRHL3 promotes tumor growth and metastasis via the MEK pathway in colorectal cancer
L Tan, W Qu, D Wu, M Liu, Q Wang, Q Ai… - Analytical Cellular …, 2021 - Wiley Online Library
GRHL3 is a factor associated with a tumor, of which the molecular mechanism remains a
further investigation. We explored the underlying mechanism of tumor‐promoting effect of …
further investigation. We explored the underlying mechanism of tumor‐promoting effect of …
[HTML][HTML] Grainyhead-like 2 promotes tumor growth and is associated with poor prognosis in colorectal cancer
Y Quan, M Xu, P Cui, M Ye, B Zhuang, Z Min - Journal of Cancer, 2015 - ncbi.nlm.nih.gov
GRHL2 was implicated in regulating cancer development. Our previous study demonstrated
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
Grhl3 induces human epithelial tumor cell migration and invasion via downregulation of E-cadherin
P Zhao, S Guo, Z Tu, L Di, X Zha, H Zhou… - … Biochim Biophys Sin, 2016 - academic.oup.com
Grainyhead genes are involved in wound healing and developmental neural tube closure.
Metastasis is a multistep process during which cancer cells disseminate from the site of …
Metastasis is a multistep process during which cancer cells disseminate from the site of …
Dual role of GRHL3 in bladder carcinogenesis depending on histological subtypes
FC Lammert, J Pannhausen, E Noetzel… - Molecular …, 2024 - Wiley Online Library
The effect of grainyhead‐like transcription factor 3 (GRHL3) on cancer development
depends on the cancer subtypes as shown in tumor entities such as colorectal or oral …
depends on the cancer subtypes as shown in tumor entities such as colorectal or oral …
Grainyhead-like 3 influences migration and invasion of urothelial carcinoma cells
F Wezel, J Lustig, A Azoitei, J Liu, S Meessen… - International journal of …, 2021 - mdpi.com
Invasive urothelial carcinomas of the bladder (UCB) characteristically show a loss of
differentiation markers. The transcription factor Grainyhead-like 3 (GRHL3) plays an …
differentiation markers. The transcription factor Grainyhead-like 3 (GRHL3) plays an …