Hemophagocytic lymphohistiocytosis (HLH) is a rare life‐threatening disease in which the
immune system becomes overactive due to its inability to effectively respond to infections …

Hemophagocytic lymphohistiocytosis (HLH) covers a wide array of related life-threatening
conditions featuring ineffective immunity characterized by an uncontrolled …

Several key molecular events have been defined which lead to a final common etiologic
pathway of natural killer cell dysfunction leading to the hemophagocytic lymphohistiocytosis …

Hemophagocytic lymphohistiocytosis (HLH) is not an independent disease but rather a life-
threatening clinical syndrome that occurs in many underlying conditions and in all age …

Hemophagocytic lymphohistiocytosis (HLH) is a disorder that has been recognized since the
middle of the last century. In recent decades, increasing understanding of the genetic roots …

Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder with familial and acquired
forms. The familial form is associated with mutations in the perforin gene and both forms are …

Hemophagocytic lymphohistiocytosis (HLH) is an overwhelming clinical syndrome
associated with extreme immune activation. Familial HLH is caused by autosomal-recessive …

Context.—Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder of
immune regulation that can eventually result in end-organ damage and death. HLH is …

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease of
hyperinflammation resulting from immune dysregulation due to inherited defects in the …

Hemophagocytic lymphohistiocytosis is a life-threatening disorder characterized by
unbridled activation of cytotoxic T lymphocytes, natural killer (NK) cells, and macrophages …