Hepatoprotective activity of chrysin is mediated through TNF-α in chemically-induced acute liver damage: An in vivo study and molecular modeling
A Hermenean, T Mariasiu… - Experimental and …, 2017 - spandidos-publications.com
Abstract Chrysin (5, 7-dihydroxyflavone) is a naturally occurring flavonoid present at high
levels in honey, propolis and numerous plant extracts. Chrysin is known to have …
levels in honey, propolis and numerous plant extracts. Chrysin is known to have …
A comprehensive review on hepatoprotective and nephroprotective activities of chrysin against various drugs and toxic agents
Chrysin belongs to the flavonoids and has been used as traditional medicine from ancient
and has been reported to exhibit a wide range of pharmacological properties. The …
and has been reported to exhibit a wide range of pharmacological properties. The …
Cyanidin Alleviated CCl4-Induced Acute Liver Injury by Regulating the Nrf2 and NF-κB Signaling Pathways
B Wang, S Cui, B Mao, Q Zhang, F Tian, J Zhao… - Antioxidants, 2022 - mdpi.com
Acute liver injury has multiple causes and can result in liver failure. In this study, we
evaluated the hepatoprotective ability of cyanidin (Cy) and investigated its associated …
evaluated the hepatoprotective ability of cyanidin (Cy) and investigated its associated …
Chrysin effect in prevention of acetaminophen-induced hepatotoxicity in rat
A Mohammadi, S Kazemi, M Hosseini… - Chemical Research …, 2019 - ACS Publications
Acetaminophen is a commonly used analgesic drug that induces hepatotoxicity at high
doses and produces the acetaminophen metabolite N-acetyl-p-benzoquinone imine …
doses and produces the acetaminophen metabolite N-acetyl-p-benzoquinone imine …
Chrysin attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway
We investigated the protective effect of chrysin on chronic liver fibrosis in mice and the
potential mechanism underlying TGF-β1-mediated hepatic stellate cells (HSCs) activation …
potential mechanism underlying TGF-β1-mediated hepatic stellate cells (HSCs) activation …
Alleviation of hepatic injury by chrysin in cisplatin administered rats: probable role of oxidative and inflammatory markers
Background Cisplatin is an effective and extensively used chemotherapeutic agent to treat
range of malignancies, but its therapeutic use is limited because of dose-dependent …
range of malignancies, but its therapeutic use is limited because of dose-dependent …
Chrysin mitigates diclofenac-induced hepatotoxicity by modulating oxidative stress, apoptosis, autophagy and endoplasmic reticulum stress in rats
Background Diclofenac (DF) is a non-steroidal anti-inflammatory drug (NSAID) generally
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …
Novel antioxidant, deethylated ethoxyquin, protects against carbon tetrachloride induced hepatotoxicity in rats by inhibiting NLRP3 inflammasome activation and …
IY Iskusnykh, ED Kryl'skii, DA Brazhnikova, TN Popova… - Antioxidants, 2021 - mdpi.com
Inflammation and an increase in antioxidant responses mediated by oxidative stress play an
important role in the pathogenesis of acute liver injury (ALI). We utilized in silico prediction of …
important role in the pathogenesis of acute liver injury (ALI). We utilized in silico prediction of …
[HTML][HTML] Breviscapine ameliorates CCl4‑induced liver injury in mice through inhibiting inflammatory apoptotic response and ROS generation
Y Liu, PH Wen, XX Zhang, Y Dai… - … journal of molecular …, 2018 - spandidos-publications.com
Acute liver injury is characterized by fibrosis, inflammation and apoptosis, leading to liver
failure, cirrhosis or cancer and affecting the clinical outcome in the long term. However, no …
failure, cirrhosis or cancer and affecting the clinical outcome in the long term. However, no …
Quercetin prevents pyrrolizidine alkaloid clivorine-induced liver injury in mice by elevating body defense capacity
L Ji, Y Ma, Z Wang, Z Cai, C Pang, Z Wang - PLoS One, 2014 - journals.plos.org
Quercetin is a plant-derived flavonoid that is widely distributed in nature. The present study
is designed to analyze the underlying mechanism in the protection of quercetin against …
is designed to analyze the underlying mechanism in the protection of quercetin against …