A myriad of proteins and peptides can be identified in normal human urine. These are
derived from a variety of sources including glomerular filtration of blood plasma, cell …

For centuries, physicians have attempted to use the urine for noninvasive assessment of
disease. Today, urinalysis, in particular the measurement of proteinuria, underpins the …

Introduction: Urine is a highly desirable biospecimen for biomarker analysis because it can
be collected recurrently by non-invasive techniques, in relatively large volumes. Urine …

Abstract Knowledge of the biologically relevant components of human tissues has enabled
the invention of numerous clinically useful diagnostic tests, as well as non‐invasive ways of …

Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …

The abundance profile of the human urinary proteome is known to change as a result of
diseases or drug toxicities, particularly of those affecting the kidney and the urogenital tract …

Because of its availability, ease of collection, and correlation with physiology and pathology,
urine is an attractive source for clinical proteomics/peptidomics. However, the lack of …

Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or
ultracentrifugation. Background Proteomic techniques have recently become available for …

Biomarkers are measurable changes associated with the disease. Urine can reflect the
changes of the body while blood is under control of the homeostatic mechanisms; thus, urine …

The success of clinical proteome analysis should be assessed based on the clinical impact
following implementation of findings. Although there have been several technological …