Estrogen in females is conventionally considered a cardioprotective influence, but a role for
estrogen in male cardioprotection has yet to be defined. Estrogen biosynthesis from …

Steroid hormones appear to be a key factor in the gender differences in the rates and
severity of cardiovascular diseases. Aldosterone and testosterone have typical steroid ring …

While the gender bias associated with coronary artery disease has been suggested to be
partially accounted for by the protective effects of oestrogens, the role of testosterone …

The conventional view is that estrogen confers female cardioprotection. Estrogen synthesis
depends on androgen availability, with aromatase regulating conversion of testosterone to …

The greater incidence of coronary artery disease in men compared to women has often
suggested possible harmful effects of male sex steroids that could promote coronary …

After menopause, the development of cardiovascular disease (CVD) is due not only to
estrogen decline but also to androgen decline. This study examined the effects of either …

The molecular and pharmacological manipulation of the endogenous redox system is a
promising therapy to limit myocardial damage after a heart attack; however, antioxidant …

Recent clinical studies have reported that testosterone therapy reduces myocardial
ischaemia in men with coronary artery disease, and the beneficial modulation of coronary …

In this work we studied the influence of sex hormones on heart and mitochondrial functions,
from adult castrated female and male, and intact rats. Castration was performed at their third …

Evidence supports that oxidative stress exerts significant effects on the pathogenesis of
heart dysfunction. On the other hand, the presence of specific androgen receptor (AR) in …