Our recent studies, in vitro, with bromelain, a natural product, indicated specific retardation of
Lewis lung carcinoma, YC-8 lymphoma, and MCA-1 ascitic tumor cells (1) as well as a …

The antitumor and antimetastatic activities of the plant cysteine endoproteinase bromelaine
were evaluated in a murine model. Syngeneic sarcoma L-1 cells were incubated with …

Abstract Stem bromelain (EC 3.4. 22.32) is a major cysteine proteinase, isolated from
pineapple (Ananas comosus) stem. Its main medicinal use is recognized as digestive, in …

Bromelain, a pineapple-derived plant product, added to C57B1/6 mice laboratory chow
decreased lung metastasis of Lewis lung cancer cells implanted sc This antimetastatic …

Non steroidal anti-inflammatory drugs such as aspirin and indomethacin associated with
inhibition of platelet aggregation (1, 2, 3) have been reported to retard tumour growth (4) …

The abilities of the Eli Lilly compounds LY150310, LY189332, and LY135305 to inhibit
spontaneous metastasis and to increase animal survival were evaluated. These compounds …

Several polyphenolic compounds were tested for the inhibition of lung metastasis induced
by B16F10 melanoma cells in mice. Oral administration of polyphenols such as curcumin …

We examined the effect of berberine, a major component with anti-fungal properties
contained in Coptidis Rhizoma and Phellodendri Cortex, on the lymph node metastasis of …

The effects of naturally occurring monoterpenes on lung metastasis induced by B16F-10
melanoma cells were studied in C57BL/6 mice. Administration of monoterpenes such as …

Methods The testing of the conifers was carried out as described previously (1). An aqueous
suspension of dried, powdered leaves was injected in a dose of 1 mg. per gm …