Mitochondria are dynamic cellular organelles that consistently migrate, fuse, and divide to
modulate their number, size, and shape. In addition, they produce ATP, reactive oxygen …

Dysfunctional mitochondria are thought to play a cardinal role in the pathogenesis of various
neurological disorders, such as multiple sclerosis, Alzheimer's disease, Parkinson's disease …

Neurodegenerative diseases are a heterogeneous group of disorders that are incurable and
characterized by the progressive degeneration of the function and structure of the central …

Age is the main risk factor for a number of human diseases, including neurodegenerative
disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral …

Mitochondria are involved in ATP supply to cells through oxidative phosphorylation
(OXPHOS), synthesis of key molecules and response to oxidative stress, as well as in …

Mitochondria play a critical role in several metabolic processes and apoptotic pathways,
regulating life cycle from the cradle to the grave. Despite the evidence of morphological …

Mitochondrial dysfunction is central to the pathogenesis of neurological disorders. Neurons
rely on oxidative phosphorylation to meet their energy requirements and thus alterations in …

Mitochondrial function is vital for normal cellular processes. Mitochondrial damage and
oxidative stress have been greatly implicated in the progression of aging, along with the …

Mitochondria are implicated in several metabolic pathways including cell respiratory
processes, apoptosis, and free radical production. Mitochondrial abnormalities have been …

Fundamental organelles that occur in every cell type with the exception of mammal
erythrocytes, the mitochondria are required for multiple pivotal processes that include the …