Toll like receptor-3 priming alters diesel exhaust particle-induced cytokine responses in human bronchial epithelial cells
Inflammation is considered central in the pathology of health effects from airborne particulate
matter (PM). Preexisting inflammatory disorders, such as asthma, but also pulmonary …
matter (PM). Preexisting inflammatory disorders, such as asthma, but also pulmonary …
Route of exposure alters inflammation and lung function responses to diesel exhaust
Context: Mice are commonly used in studies investigating the effects of diesel exhaust
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …
Nitric oxide and superoxide mediate diesel particle effects in cytokine-treated mice and murine lung epithelial cells—implications for susceptibility to traffic-related air …
ND Manzo, AJ LaGier, R Slade, AD Ledbetter… - Particle and fibre …, 2012 - Springer
Background Epidemiologic studies associate childhood exposure to traffic-related air
pollution with increased respiratory infections and asthmatic and allergic symptoms. The …
pollution with increased respiratory infections and asthmatic and allergic symptoms. The …
Chronic exposure of diesel exhaust particles induces alveolar enlargement in mice
Abstract Background Diesel exhaust particles (DEPs) are deposited into the respiratory tract
and are thought to be a risk factor for the development of diseases of the respiratory system …
and are thought to be a risk factor for the development of diseases of the respiratory system …
Effect of ozone on diesel exhaust particle toxicity in rat lung
MC Madden, JH Richards, LA Dailey, GE Hatch… - Toxicology and applied …, 2000 - Elsevier
Ambient particulate matter (PM) concentrations have been associated with mortality and
morbidity. Diesel exhaust particles (DEP) are present in ambient urban air PM. Coexisting …
morbidity. Diesel exhaust particles (DEP) are present in ambient urban air PM. Coexisting …
Time-course effects of systemically administered diesel exhaust particles in rats
Nanosized fraction of particulate air pollution has been reported to translocate from the
airways into the bloodstream and act on different organs. However, the direct effect of these …
airways into the bloodstream and act on different organs. However, the direct effect of these …
Enhancement of allergic inflammation by diesel exhaust particles: permissive role of reactive oxygen species
AM Casillas, T Hiura, N Li, AE Nel - Annals of Allergy, Asthma & …, 1999 - Elsevier
BACKGROUND: Diesel emission particulates (DEP) exert effects on the immune system and
act as an adjuvant which enhances allergic inflammation. Animal and human models have …
act as an adjuvant which enhances allergic inflammation. Animal and human models have …
Chemical characterization and in vitro toxicity of diesel exhaust particulate matter generated under varying conditions
JR Fox, DP Cox, BE Drury, TR Gould… - Air Quality, Atmosphere …, 2015 - Springer
Epidemiologic studies have linked diesel exhaust (DE) to cardiovascular and respiratory
morbidity and mortality, as well as lung cancer. DE composition is known to vary with many …
morbidity and mortality, as well as lung cancer. DE composition is known to vary with many …
Diesel exhaust particles suppress macrophage function and slow the pulmonary clearance of Listeria monocytogenes in rats.
HM Yang, JM Antonini, MW Barger… - Environmental …, 2001 - ehp.niehs.nih.gov
In this study, we tested the hypothesis that exposure to diesel exhaust particles (DEP) may
increase susceptibility of the host to pulmonary infection. Male Sprague-Dawley rats …
increase susceptibility of the host to pulmonary infection. Male Sprague-Dawley rats …
cDNA microarray analysis of gene expression in rat alveolar macrophages in response to organic extract of diesel exhaust particles
E Koike, S Hirano, N Shimojo… - Toxicological …, 2002 - academic.oup.com
Diesel exhaust particles (DEP) induce pulmonary diseases including asthma and chronic
bronchitis. Comprehensive evaluation is required to know the effects of pollutants including …
bronchitis. Comprehensive evaluation is required to know the effects of pollutants including …