Toll like receptor-3 priming alters diesel exhaust particle-induced cytokine responses in human bronchial epithelial cells

NS Bach, M Låg, J Øvrevik - Toxicology letters, 2014 - Elsevier
Inflammation is considered central in the pathology of health effects from airborne particulate
matter (PM). Preexisting inflammatory disorders, such as asthma, but also pulmonary …

Route of exposure alters inflammation and lung function responses to diesel exhaust

AN Larcombe, JA Phan, A Kicic, KL Perks… - Inhalation …, 2014 - Taylor & Francis
Context: Mice are commonly used in studies investigating the effects of diesel exhaust
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …

Nitric oxide and superoxide mediate diesel particle effects in cytokine-treated mice and murine lung epithelial cells—implications for susceptibility to traffic-related air …

ND Manzo, AJ LaGier, R Slade, AD Ledbetter… - Particle and fibre …, 2012 - Springer
Background Epidemiologic studies associate childhood exposure to traffic-related air
pollution with increased respiratory infections and asthmatic and allergic symptoms. The …

Chronic exposure of diesel exhaust particles induces alveolar enlargement in mice

K Yoshizaki, JM Brito, HT Moriya, AC Toledo… - Respiratory …, 2015 - Springer
Abstract Background Diesel exhaust particles (DEPs) are deposited into the respiratory tract
and are thought to be a risk factor for the development of diseases of the respiratory system …

Effect of ozone on diesel exhaust particle toxicity in rat lung

MC Madden, JH Richards, LA Dailey, GE Hatch… - Toxicology and applied …, 2000 - Elsevier
Ambient particulate matter (PM) concentrations have been associated with mortality and
morbidity. Diesel exhaust particles (DEP) are present in ambient urban air PM. Coexisting …

Time-course effects of systemically administered diesel exhaust particles in rats

A Nemmar, S Al-Salam, S Zia, S Dhanasekaran… - Toxicology letters, 2010 - Elsevier
Nanosized fraction of particulate air pollution has been reported to translocate from the
airways into the bloodstream and act on different organs. However, the direct effect of these …

Enhancement of allergic inflammation by diesel exhaust particles: permissive role of reactive oxygen species

AM Casillas, T Hiura, N Li, AE Nel - Annals of Allergy, Asthma & …, 1999 - Elsevier
BACKGROUND: Diesel emission particulates (DEP) exert effects on the immune system and
act as an adjuvant which enhances allergic inflammation. Animal and human models have …

Chemical characterization and in vitro toxicity of diesel exhaust particulate matter generated under varying conditions

JR Fox, DP Cox, BE Drury, TR Gould… - Air Quality, Atmosphere …, 2015 - Springer
Epidemiologic studies have linked diesel exhaust (DE) to cardiovascular and respiratory
morbidity and mortality, as well as lung cancer. DE composition is known to vary with many …

Diesel exhaust particles suppress macrophage function and slow the pulmonary clearance of Listeria monocytogenes in rats.

HM Yang, JM Antonini, MW Barger… - Environmental …, 2001 - ehp.niehs.nih.gov
In this study, we tested the hypothesis that exposure to diesel exhaust particles (DEP) may
increase susceptibility of the host to pulmonary infection. Male Sprague-Dawley rats …

cDNA microarray analysis of gene expression in rat alveolar macrophages in response to organic extract of diesel exhaust particles

E Koike, S Hirano, N Shimojo… - Toxicological …, 2002 - academic.oup.com
Diesel exhaust particles (DEP) induce pulmonary diseases including asthma and chronic
bronchitis. Comprehensive evaluation is required to know the effects of pollutants including …