Induction of Inflammatory Response of Mice Exposed to Diesel Exhaust Is Modulated by CD4+ and CD8+ T Cells
H Fujimaki, N Ui, T Endo - … journal of respiratory and critical care …, 2001 - atsjournals.org
Exposure to diesel exhaust (DE) increased airway inflammatory responses and airway
responsiveness to allergen challenge. To clarify the roles of T cells in DE exposure–induced …
responsiveness to allergen challenge. To clarify the roles of T cells in DE exposure–induced …
Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo
Background Inhalation of diesel exhaust impairs vascular function in man, by a mechanism
that has yet to be fully established. We hypothesised that pulmonary exposure to diesel …
that has yet to be fully established. We hypothesised that pulmonary exposure to diesel …
Microarray analysis of gene expression in rat alveolar epithelial cells exposed to fractionated organic extracts of diesel exhaust particles
S Omura, E Koike, T Kobayashi - Toxicology, 2009 - Elsevier
Diesel exhaust particles (DEP) affect health adversely. Our previous studies revealed that
DEP extracts up-regulated expression of genes related to drug metabolism, antioxidant …
DEP extracts up-regulated expression of genes related to drug metabolism, antioxidant …
Response of pulmonary cellular defenses to the inhalation of high concentrations of diesel exhaust
KA Strom - Journal of Toxicology and Environmental Health, Part A …, 1984 - Taylor & Francis
Rats were exposed to three concentrations of diluted diesel exhaust for 6 mo and 1 yr.
Bronchopulmonary lavage was used to obtain the pulmonary phagocytes from the animals …
Bronchopulmonary lavage was used to obtain the pulmonary phagocytes from the animals …
Activation of pulmonary dendritic cells and Th2-type inflammatory responses on instillation of engineered, environmental diesel emission source or ambient air …
GFG Bezemer, SM Bauer, G Oberdörster… - Journal of innate …, 2011 - karger.com
The biological effects of acute particulate air pollution exposure in host innate immunity
remain obscure and have relied largely on in vitro models. We hypothesized that single …
remain obscure and have relied largely on in vitro models. We hypothesized that single …
DIESEL particulate exposed macrophages alter endothelial cell expression of eNOS, iNOS, MCP1, and glutathione synthesis genes
There is considerable debate regarding inhaled diesel exhaust particulate (DEP) causing
impairments in vascular reactivity. Although there is evidence that inhaled particles can …
impairments in vascular reactivity. Although there is evidence that inhaled particles can …
Suppression of Cell-Mediated Immune Responses to Listeria Infection by Repeated Exposure to Diesel Exhaust Particles in Brown Norway Rats
XJ Yin, CC Dong, JYC Ma, JM Antonini… - Toxicological …, 2004 - academic.oup.com
Diesel exhaust particles (DEP) have been shown to alter pulmonary immune responses to
bacterial infection. Exposure of rats to 100 mg/m3 DEP for 4 h was found to aggravate …
bacterial infection. Exposure of rats to 100 mg/m3 DEP for 4 h was found to aggravate …
Diesel exhaust particles and carbon black have adjuvant activity on the local lymph node response and systemic IgE production to ovalbumin
M Løvik, AK Høgseth, PI Gaarder, R Hagemann, I Eide - Toxicology, 1997 - Elsevier
The possible adjuvant effect of diesel exhaust particles (DEP) on the response to the model
allergen ovalbumin (OA) was studied in BALB/c mice using the popliteal lymph node (PLN) …
allergen ovalbumin (OA) was studied in BALB/c mice using the popliteal lymph node (PLN) …
Diesel exhaust particles induce CYP1A1 and pro-inflammatory responses via differential pathways in human bronchial epithelial cells
AI Totlandsdal, FR Cassee, P Schwarze… - Particle and fibre …, 2010 - Springer
Background Exposure to diesel engine exhaust particles (DEPs) has been associated with
several adverse health outcomes in which inflammation seems to play a key role. DEPs …
several adverse health outcomes in which inflammation seems to play a key role. DEPs …
Time course of gene expression of inflammatory mediators in rat lung after diesel exhaust particle exposure
KMK Rao, JYC Ma, T Meighan… - Environmental …, 2005 - ehp.niehs.nih.gov
Diesel exhaust particles (DEPs) at three concentrations (5, 35, and 50 mg/kg body weight)
were instilled into rats intratracheally. We studied gene expression at 1, 7, and 30 days …
were instilled into rats intratracheally. We studied gene expression at 1, 7, and 30 days …