Editorial Views animals with DNase in order to degrade NeTs, they observed no significant
impact on lung injury in their model. The detection of NeTs, especially in vivo, remains …

Background: Mechanical ventilation can injure the lung and induce a proinflammatory state;
such ventilator-induced lung injury (VILI) is associated with neutrophil influx. Neutrophils …

Abstract Editor's Perspective What We Already Know about This Topic Neutrophil
extracellular traps are increasingly recognized as pathogenic in acute injury, but their role in …

Background There is little knowledge, whether in patients with sepsis neutrophil
extracellular trap (NET) formation and NET degrading nuclease activity are altered. Thus, we …

Purpose Patients in whom neutropenia recovery is complicated by pneumonia have an
increased risk of acute lung injury (ALI) and detrimental outcomes. The aim of the present …

IMPLICATIONS: Acute respiratory failure is characterized by severe decreases in blood
oxygen. The pattern of blood flow within the lungs can contribute to this problem. This study …

Acute respiratory distress syndrome (ARDS) is a devastating clinical condition common in
patients with respiratory failure in the intensive care unit. It is associated with high mortality …

Background Alveolar overdistension and repetitive derecruitment-recruitment contribute to
ventilator-induced lung injury (VILI). The authors investigated (1) whether inflammatory cell …

Abstract Background Neutrophil extracellular traps (NETs) facilitate bacterial clearance but
also promote thrombosis and organ injury in sepsis. We quantified ex vivo NET induction in …

MD, Ph. D., investigates strategies to dampen ischemiadriven inflammation of the kidneys
and subsequent multiorgan failure using experimental models of acute kidney injury (AKI). In …