Surface functionalization of mesoporous silica nanoparticles controls loading and release behavior of mitoxantrone

A Wani, E Muthuswamy, GHL Savithra, G Mao… - Pharmaceutical …, 2012 - Springer
Purpose To investigate the effect of surface functionalization of mesoporous silica
nanoparticles (MSN) on crystallization, loading, release and activity of mitoxantrone (MTX) …

[HTML][HTML] Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells

A Wani, GHL Savithra, A Abyad, S Kanvinde, J Li… - Scientific reports, 2017 - nature.com
Mesoporous silica nanomaterials show great potential to deliver chemotherapeutics for
cancer treatment. The key challenges in the development of injectable mesoporous silica …

pH-responsive mitoxantrone (MX) delivery using mesoporous silica nanoparticles (MSN)

Y Ma, L Zhou, H Zheng, L Xing, C Li, J Cui… - Journal of Materials …, 2011 - pubs.rsc.org
pH-responsive mitoxantrone (MX) delivery using mesoporous silica nanoparticles (MSN) -
Journal of Materials Chemistry (RSC Publishing) DOI:10.1039/C1JM10750J Royal Society …

Indometacin loading and in vitro release properties from novel carbopol coated spherical mesoporous silica nanoparticles

B Tzankov, K Yoncheva, M Popova, A Szegedi… - Microporous and …, 2013 - Elsevier
Spherical MCM-41 silica nanosized particles were synthesized and post synthesis modified
by 3-aminopropyltriethoxysilane (APTES) in order to prepare amino-functionalized carrier …

Effect of surface functionalization and pore structure type on the release performance of mesoporous silica nanoparticles

S Peng, B Huang, Y Lin, G Pei, L Zhang - Microporous and Mesoporous …, 2022 - Elsevier
Based on the excellent physicochemical properties of mesoporous silica nanoparticles
(MSN), the application of MSN in drug delivery has become a popular strategy. However, a …

[HTML][HTML] Effect of shape on mesoporous silica nanoparticles for oral delivery of indomethacin

W Zhang, N Zheng, L Chen, L Xie, M Cui, S Li, L Xu - Pharmaceutics, 2018 - mdpi.com
The use of mesoporous silica nanoparticles (MSNs) in the field of oral drug delivery has
recently attracted greater attention. However, there is still limited knowledge about how the …

Controlled release of silyl ether camptothecin from thiol-ene click chemistry-functionalized mesoporous silica nanoparticles

Y Yan, J Fu, T Wang, X Lu - Acta biomaterialia, 2017 - Elsevier
As efficient drug carriers, stimuli-responsive mesoporous silica nanoparticles are at the
forefront of research on drug delivery systems. An acid-responsive system based on silyl …

Synthesis and characterization of core-shell mesoporous silica nanoparticles with various shell thickness as indomethacin carriers: In vitro and in vivo evaluation

J Ke, Y Wang, L Wang, B Yang, K Gou, Y Qin… - Microporous and …, 2020 - Elsevier
A series of core-shell mesoporous silica nanoparticles (MSN@ Ms) were successfully
prepared with reducing response environmental stimuli TEOS-BTES as a shell and …

Modifying mesoporous silica nanoparticles to avoid the metabolic deactivation of 6-mercaptopurine and methotrexate in combinatorial chemotherapy

W Wang, C Fang, X Wang, Y Chen, Y Wang, W Feng… - Nanoscale, 2013 - pubs.rsc.org
Mesoporous silica nanoparticles with amino and thiol groups (MSNSN) were prepared and
covalently modified with methotrexate and 6-mercaptopurine to form 6-MP–MSNSN–MTX. In …

Ultra-small mesoporous silica nanoparticles as efficient carriers for pH responsive releases of anti-cancer drugs

H Zheng, CW Tai, J Su, X Zou, F Gao - Dalton Transactions, 2015 - pubs.rsc.org
Mesoporous silica has emerged as one of the most promising carriers for drug delivery
systems. However, the synthesis of ultra-small mesoporous silica nanoparticles (UMSNs) …