Publisher Summary Several new mechanisms for the therapy of diabetes show considerable
promise for the expansion of the clinical options for the treatment of hyperglycemia. As new …

Publisher Summary This chapter focuses on advances in therapeutic approaches to type 2
diabetes. In the US, about 10% of the diabetic population suffers from Type 1 diabetes, an …

Diabetes mellitus (DM) is a progressive disease characterized by insulin deficiency and
insulin resistance or both. The fasting and post-prandial blood glucose is elevated, exposing …

Publisher Summary Although numerous mechanistic approaches to achieving improved
metabolic control in both insulin-dependent diabetic (IDDM) and noninsulin-dependent …

PREVIEW Our ability to gain strict glycemic control in diabetes has improved with the
introduction of novel insulins. New formulations, novel insulin molecules, and various …

Diabetes mellitus is a pathologic condition characterized by chronic hyperglycemia
(elevated blood glucose) and additional disturbances of carbohydrate, fat, and protein …

Insulin is one of the oldest and best studied treatments for diabetes mellitus. Despite many
improvements in the management of diabetes, the nonphysiological time-action profiles of …

Insulin and Hypoglycemic Agents - Sleevi - Major Reference Works - Wiley Online Library
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The discovery of insulin is one of the greatest milestones in medical history. This discovery
revolutionized the use of peptides and proteins as therapeutic agents. For more than six …

The first therapeutic use of insulin by Frederick Banting and Charles Best in 1921
revolutionized the management of type 1 diabetes and considerably changed the lives of …