Discovering cross-reactivity in urine drug screening immunoassays through large-scale analysis of electronic health records

JJ Hughey, JM Colby - Clinical Chemistry, 2019 - academic.oup.com
BACKGROUND Exposure to drugs of abuse is frequently assessed using urine drug
screening (UDS) immunoassays. Although fast and relatively inexpensive, UDS assays …

Clinical interpretation of urine drug tests: what clinicians need to know about urine drug screens

KE Moeller, JC Kissack, RS Atayee, KC Lee - Mayo Clinic Proceedings, 2017 - Elsevier
Urine drug testing is frequently used in clinical, employment, educational, and legal settings
and misinterpretation of test results can result in significant adverse consequences for the …

Provider misinterpretation, documentation, and follow-up of definitive urine drug testing results

I Chua, AK Petrides, GD Schiff, JR Ransohoff… - Journal of general …, 2020 - Springer
Background Urine drug testing (UDT) is an essential tool to monitor opioid misuse among
patients on chronic opioid therapy. Inaccurate interpretation of UDT can have deleterious …

[PDF][PDF] Urine drug testing: approaches to screening and confirmation testing

G Lum, B Mushlin - Laboratory Medicine, 2004 - scholar.archive.org
• Detectable in urine for relatively long period of time• Presence of metabolites (in addition to
parent drug) provides further evidence of drug use• Readily preserved by refrigeration or …

Laboratory and clinical evaluation of on-site urine drug testing

O Beck, S Carlsson, M Tusic, R Olsson… - … Journal of Clinical …, 2014 - Taylor & Francis
Aim. Products for on-site urine drug testing offer the possibility to perform screening for drugs
of abuse directly at the point-of-care. This is a well-established routine in emergency and …

Comparison of LUCIO®‐direct ELISA with CEDIA immunoassay for 'zero tolerance'drug screening in urine as required by the German re‐licensing guidelines

R Agius, T Nadulski, HG Kahl… - Drug testing and …, 2013 - Wiley Online Library
The performance of the previously validated LUCIO®‐Direct‐enzyme linked immunosorbent
assay (direct ELISA) screening tests according to forensic guidelines is compared to that of …

Lack of detection of new amphetamine-like drugs using conventional urinary immunoassays

A Begeman, EJF Franssen - Therapeutic Drug Monitoring, 2018 - journals.lww.com
Background: The number of reports of serious adverse effects and intoxication after the use
of the new drug 4-fluoroamphetamine (4-FA) increases. At the Emergency Department of the …

Analytic performance of immunoassays for drugs of abuse below established cutoff values

VI Luzzi, AN Saunders, JW Koenig, J Turk… - Clinical …, 2004 - academic.oup.com
Background: The analytic performance and accuracy of drug detection below Substance
Abuse and Mental Health Services Administration (SAMHSA) cutoffs is not well known. In …

Challenges in urine bioanalytical assays: overcoming nonspecific binding

AJ Ji, Z Jiang, Y Livson, JA Davis, JX Chu, N Weng - Bioanalysis, 2010 - Taylor & Francis
Dr Allena Ji is the Director of Bioanalytical Services, XenoBiotic Laboratories, Inc., NJ, USA.
She has worked in the bioanalytical field for many years and accumulated rich experience in …

False-positive amphetamines in urine drug screens: a 6-year review

JD Pope, OH Drummer… - Journal of Analytical …, 2023 - academic.oup.com
Immunoassays are routinely used to provide rapid urine drug screening results in the clinical
setting. These screening tests are prone to false-positive results and ideally require …