Recent studies have provided evidence to suggest a possible role for mucosal immune
activation in the pathophysiology of irritable bowel syndrome (IBS). On the other hand, novel …

Recent reports have emphasized the possible role of mucosal immune activation and
inflammation in neuropathic changes in the pathophysiology of irritable bowel syndrome …

Chronic abdominal pain is a common symptom of great clinical significance in several areas
of medicine. In many cases no organic cause can be established resulting in the …

Irritable bowel syndrome (IBS) is a functional, multifactorial disease characterized by
abdominal pain and erratic bowel habit. Changes in gastrointestinal motor function …

Converging evidence supports the concept that the irritable bowel syndrome (IBS) symptom
complex results from altered regulation of gastrointestinal motility and epithelial function, as …

Attention has been directed to the putative role of low grade mucosal inflammation in
irritable bowel syndrome (IBS) on the basis of evidence showing that some patients with IBS …

The observations that irritable bowel syndrome (IBS) may be precipitated by an acute enteric
infection, or occurs commonly in patients in remission from inflammatory bowel disease …

Growing evidence suggests that symptoms in patients with irritable bowel syndrome (IBS)
may be due to a visceral sensory dysfunction. Specifically, it has been shown that patients …

There is considerable interest in the mechanisms that underlie symptom generation in
irritable bowel syndrome (IBS) and particularly those mechanisms peripheral to higher …

Both irritable bowel syndrome and inflammatory bowel diseases share symptoms of altered
bowel habits associated with abdominal pain or discomfort. Irritable bowel syndrome has …