One of the hallmarks of cancer is the deregulation of cellular energetics [1]. This allows
cancer cells to proliferate and survive in microenvironments that would lead to the death of a …

Reactive oxygen species (ROS) are important in regulating normal cellular processes, but
deregulated ROS contribute to the development of various human diseases, including …

Increased oxidative stress is a common feature observed in many different types of cancer.
Depending on the radical formed, its concentration, and cellular location where its …

The regulation of oxidative stress is an important factor in both tumour development and
responses to anticancer therapies. Many signalling pathways that are linked to …

Reactive oxygen species (ROS) are important in regulating normal cellular processes
whereas deregulated ROS leads to the development of a diseased state in humans …

It is well known that species derived from oxygen are cytotoxic and are involved in the
etiology of cancer. Several carcinogens during metabolism exert their effect by producing …

Cancer cells are characterized by an increase in the rate of reactive oxygen species (ROS)
production and an altered redox environment compared to normal cells. Furthermore, redox …

Cancer remains the second leading cause of death worldwide. Research is currently
focused on finding novel anticancer therapies and elucidating their mechanisms of action …

Reactive oxygen species (ROS) constantly generated inside the body are required to drive
regulatory pathways and are also a cause for several pathological conditions including …

Significance: Reactive oxygen species (ROS) are generated during mitochondrial oxidative
metabolism, and are tightly controlled through homeostatic mechanisms to maintain …