Recent articles in this journal suggest a new role for HDL in endothelial progenitor cell
(EPC)-mediated endothelial repair. 1, 2 We investigated the effect of increasing HDL levels …

Recently we identified hypoxia‐inducible protein 2 (HIG2)/hypoxia‐inducible lipid droplet–
associated (HILPDA) as lipid droplet (LD) protein. Because HILPDA is highly expressed in …

Background and aims The relationships between very high plasma HDLc and subclinical
atherosclerosis are still a matter of debate. Methods and results Twenty subjects with …

Introduction: Mitochondrial aldehyde dehydrogenase (ALDH-2) plays a major role in the
ethanol detoxification pathway by removing acetaldehyde. Therefore, ALDH-2 inhibitors …

Background: Pharmacogenomic studies have shown that ADCY9 genotype determines the
effects of the CETP (cholesteryl ester transfer protein) inhibitor dalcetrapib on cardiovascular …

Aging is a complex irreversible biological process associated with increased prevalence of
chronic disease and high healthcare burden. Several theories have been proposed for the …

Aim ABCA1 protects against atherosclerosis by facilitating cholesterol efflux from
macrophage foam cells in the arterial wall to extracellular apolipoprotein (apo) AI. In contrast …

Background Members of the ALDH1 protein family, known as retinal dehydrogenases
(RALDH), produce retinoic acid (RA), a metabolite of vitamin A, and may also oxidize other …

Abstract Although histone deacetylase 6 (HDAC6) has been implicated in inflammatory
diseases, direct involvement and its action mechanism of HDAC6 in the transcriptional …

A total number of 18 different isoforms of histone deacetylases (HDACs) which were
categorized into 4 classes have been identified in human. HDAC3 is categorized as class I …